Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.70 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.64 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.60 |
| ▸ | EGFR | P00533 | 4/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2517329 | 0.93 | MAOB (0.60) | MAOBNR4A1NR4A2NR4A3PTGS1 | |
| SCHEMBL9551255 | 0.91 | MAOB (0.64) | MAOBNR4A2PARP10SMN1; SMN2L3MBTL1 | |
| SCHEMBL15596323 | 0.86 | MAOB (0.66) | MAOBNR4A1NR4A2NR4A3PTGS1 | |
| SCHEMBL5386288 | 0.85 | NR4A1 (0.68) | MAOBNR4A1NR4A2NR4A3PTGS1 | |
| SCHEMBL19157998 | 0.83 | MAOB (0.61) | MAOBNR4A1NR4A2NR4A3PTGS1 | |
| SCHEMBL13703984 | 0.82 | MEN1 (0.54) | MAOBNR4A1NR4A2NR4A3PTGS1 | |
| SCHEMBL5378418 | 0.82 | NR4A1 (0.64) | MAOBNR4A1NR4A2NR4A3PTGS1 | |
| SCHEMBL1229367 | 0.82 | PTGS1 (0.61) | MAOBNR4A1NR4A2NR4A3PTGS1 | |
| SCHEMBL42302 | 0.82 | MAOB (1.00) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL27604519 | 0.82 | MAOB (0.70) | MAOBNR4A1NR4A2NR4A3PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102351655-A | Synthesis method of 4-isopropylresorcinol | HANGZHOU ALLSINO CHEMICAL CO LTD | 2012-02-15 | — | — | CN | disclosed |
| EP-0979819-B1 | Process for the production of substituted 3-hydroxypiperidines | SPEEDEL PHARMA AG (CH) | 2008-04-23 | — | — | EP | disclosed |
| EP-0979824-B1 | Process for the preparation of substituted piperidine-epoxides | HOFFMANN LA ROCHE (CH) | 2004-10-06 | — | — | EP | disclosed |
| CN-1161335-C | Method for preparing substituted piperidine | - | 2004-08-11 | — | — | CN | disclosed |
| US-6274735-B1 | RENIN INHIBITORS | HOFFMANN-LA ROCHE INC. | 2001-08-14 | — | — | US | disclosed |
| US-6268499-B1 | USEFUL AS RENIN INHIBITORS | HOFFMAN-LA ROCHE INC. | 2001-07-31 | — | — | US | disclosed |
| EP-0979824-A1 | Process for the preparation of substituted piperidine-epoxides | F. HOFFMANN-LA ROCHE AG (CH) | 2000-02-16 | — | — | EP | disclosed |
| EP-0979819-A1 | Process for the production of substituted 3-hydroxypiperidines | F. HOFFMANN-LA ROCHE AG (CH) | 2000-02-16 | — | — | EP | disclosed |