Sugi Predict

Sugi Predict / Compounds / SCHEMBL42302

SCHEMBL42302

SCHEMBL42302

CC(=O)c1ccc(OCc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 14/20 1.00
▸ ALDH1A1 P00352 1/20 0.82
▸ HTT P42858 1/20 0.82
▸ SMN1; SMN2 Q16637 1/20 0.82
▸ L3MBTL1 Q9Y468 1/20 0.82
▸ NR4A1 P22736 1/20 0.74
▸ NR4A2 P43354 1/20 0.74
▸ NR4A3 Q92570 1/20 0.74
▸ MAOA P21397 2/20 0.71
▸ PARP10 Q53GL7 1/20 0.70
▸ SRD5A2 P31213 1/20 0.68
▸ PLA2G4B P0C869 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6337667 0.95 MAOB (0.90) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL9126144 0.95 MAOB (0.90) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL13513249 0.93 MAOB (0.87) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL27518404 0.92 MAOB (0.85) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL17602370 0.91 MAOB (0.82) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL11845043 0.90 MAOB (0.82) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL29154487 0.90 ALDH1A1 (0.83) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL6054433 0.90 MAOB (0.82) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL17602254 0.89 MAOB (0.80) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL17602252 0.86 MAOB (0.74) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 634 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118702556-A Method for preparing medical intermediate from lignin and application thereof 江苏大学 2024-09-27 — — CN claimed
CN-113651815-B Eudistomins Y compound, preparation method thereof and application of drug resistance reversal agent 烟台大学 2022-04-29 — — CN claimed
CN-113651815-A Eudistomins Y compound, preparation method thereof and application of drug resistance reversal agent 烟台大学 2021-11-16 — — CN claimed
CN-109020883-A A kind of 3- cyano -2-aminopyridine analog derivative and the preparation method and application thereof 广西民族大学 2018-12-18 — — CN claimed
CN-104447556-B A kind of compound with analgesic activity and preparation method thereof SOUTH-CENTRAL UNIVERSITY FOR NATIONALITIES (CN) 2016-05-18 — — CN claimed
US-20100179343-A1 METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-07-15 — — US claimed
WO-2008121074-A1 METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-10-09 — — WO claimed
US-12559455-B2 Compound as a UBR box domain ligand AUTOTAC INC. (KR) 2026-02-24 — — US disclosed
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 — — US disclosed
EP-4611747-A1 IMIDAZOLE COMPOUNDS AND THEIR USE AS SODIUM CHANNEL INHIBITORS Genep Inc. (US) 2025-09-10 — — EP disclosed
US-20250145598-A1 ACID CERAMIDASE INHIBITORS AND USES THEREOF UNIV CALIFORNIA (US) 2025-05-08 — — US disclosed
US-12286491-B2 Image forming device and image forming method RICOH COMPANY, LTD. (JP) 2025-04-29 — — US disclosed
WO-2025059538-A1 YAP DEGRADERS AS POTENTIAL ANTICANCER DRUGS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-03-20 — — WO disclosed
US-4613611-A HYPOGLYCEMIC AGENTS AMERICAN CYANAMID COMPANY (US) 1986-09-23 — — US disclosed
EP-0004835-B1 ETHANOLAMINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR MEDICINAL USE Aktiebolaget DRACO (SE) 1981-10-14 — — EP disclosed
US-4220663-A Combating pests with benzyl phenyl ethers BAYER AKTIENGESELLSCHAFT (DE) 1980-09-02 — — US disclosed
EP-0004835-A1 Ethanolamine compounds, processes for their preparation, pharmaceutical preparations containing them and their medicinal use Aktiebolaget DRACO (SE) 1979-10-17 — — EP disclosed
US-4145439-A NEMATOCIDES, FUNGICIDES, BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-03-20 — — US disclosed
US-4098816-A HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS BEECHAM GROUP LIMITED (GB) 1978-07-04 — — US disclosed
US-4038412-A ANTI-VIRAL AGENTS RICHARDSON-MERRELL INC. (US) 1977-07-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100179343-A1 METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE TDO2, AOX1, DAO MAOB 714/4885ALDH1A1 472/4885HTT 4703/4885
US-20250145598-A1 ACID CERAMIDASE INHIBITORS AND USES THEREOF ASAH2, ASAH1, ACER2 MAOB 936/4885ALDH1A1 650/4885HTT 4119/4885
US-12559455-B2 Compound as a UBR box domain ligand UBR4, UBTF, UBQLN1 MAOB 1747/4885ALDH1A1 1486/4885HTT 286/4885
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP3, DPP7, DPP9 MAOB 2171/4885ALDH1A1 341/4885HTT 1602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.