SCHEMBL4602867

SCHEMBL4602867

CC1(C)CC(Nc2nc(Cl)nc(NC3CC(C)(C)NC(C)(C)C3)n2)CC(C)(C)N1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 2/20 0.47
ALDH1A1 P00352 2/20 0.41
LMNA P02545 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
RAD52 P43351 1/20 0.41
GFER P55789 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPK14 Q16539 1/20 0.40
TSHR P16473 1/20 0.40
RAB9A P51151 1/20 0.39
KCNH2 Q12809 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
RECQL P46063 1/20 0.36
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8708517 0.96 PDE4A (0.44) PDE4AALDH1A1LMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL10898068 0.95 PDE4A (0.42) PDE4AALDH1A1LMNAMEN1KMT2A
SCHEMBL3079982 0.91 ALDH1A1 (0.47) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL9031238 0.85 PDE4A (0.39) PDE4AALDH1A1LMNAMEN1KMT2A
SCHEMBL21895102 0.84 ALDH1A1 (0.42) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL21895098 0.84 ALDH1A1 (0.42) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL8960631 0.83 ALDH1A1 (0.40) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL10444747 0.82 KMT2A (0.40) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL21894684 0.82 ALDH1A1 (0.41) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL8838292 0.82 ALDH1A1 (0.41) ALDH1A1LMNAMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5510467-A EXCELLENT AS PIGMENTS, USEFUL FOR DYEING SOLVENT-FREE OR SOLVENT CONTAINING PLASTICS SANDOZ LTD. (CH) 1996-04-23 US claimed
WO-2020058338-A1 USE OF A LOW MOLECULAR WEIGHT TRIAZINE BASED COMPOUND AS THERMAL / LIGHT STABILIZER IN POLYMERS BOREALIS AG (AT) 2020-03-26 WO disclosed
US-20080251758-A1 Triazine Compounds Comprising Substituents Containing Amino Groups and Carboxyl Groups EVONIK DEGUSSA GMBH (DE) 2008-10-16 US disclosed
EP-1948640-A2 TRIAZINE COMPOUNDS COMPRISING SUBSTITUENTS CONTAINING AMINO GROUPS AND CARBOXYL GROUPS Evonik Degussa GmbH (DE) 2008-07-30 EP disclosed
WO-2007057265-A2 TRIAZINE COMPOUNDS COMPRISING SUBSTITUENTS CONTAINING AMINO GROUPS AND CARBOXYL GROUPS EVONIK DEGUSSA GMBH (DE) 2007-05-24 WO disclosed
EP-1787989-A1 Triazine derivatives containing amino and carboxylic acic group Degussa GmbH (DE) 2007-05-23 EP disclosed
US-5696261-A Piperidine-triazine compounds suitable for use as stabilisers for organic materials CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-12-09 US disclosed
US-5489683-A HEAT RESISTANCE, OXIDATION RESISTANCE CIBA-GEIGY CORPORATION (US) 1996-02-06 US disclosed
EP-0075849-B1 TRIAZINYLLACTAMES, PROCESS FOR THEIR PREPARATION, THEIR USE AS STABILISATORS FOR SYNTHETIC ORGANIC POLYMERS AND POLYMERS STABILISED BY THEM HOECHST AKTIENGESELLSCHAFT (DE) 1987-07-22 EP disclosed
EP-0112690-B1 TRIS(PIPERIDYLAMINOTRIAZYLAMINO) COMPOUNDS, THEIR PREPARATION AND THEIR USE AS POLYMER STABILIZERS SANKYO COMPANY LIMITED (JP) 1987-04-29 EP disclosed
EP-0112690-A2 Tris(piperidylaminotriazylamino) compounds, their preparation and their use as polymer stabilizers SANKYO COMPANY LIMITED (JP) 1984-07-04 EP disclosed
EP-0075849-A2 Triazinyllactames, process for their preparation, their use as stabilisators for synthetic organic polymers and polymers stabilised by them HOECHST AKTIENGESELLSCHAFT (DE) 1983-04-06 EP disclosed
EP-0002005-B1 PROCESS FOR BLOCKING END GROUPS OF POLYMERIC POLYALKYLPIPERIDINE DERIVATIVES, THE PRODUCTS WITH BLOCKED END GROUPS THUS OBTAINED AND THEIR USE AS LIGHT STABILISERS FOR SYNTHETIC MATERIALS CIBA-GEIGY AG (CH) 1983-01-19 EP disclosed
EP-0042554-A1 Polytriazinyl amines, process for their preparation, their use as stabilizing agents for synthetic polymers and polymers stabilized with these compounds HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-30 EP disclosed
US-4263434-A UV STABILIZERS FOR POLYMERS CHIMOSA CHIMICA ORGANICA S.P.A. (IT) 1981-04-21 US disclosed
US-4234707-A Polymeric light stabilizers for plastics CIBA-GEIGY CORPORATION (US) 1980-11-18 US disclosed
EP-0002005-A1 Process for blocking end groups of polymeric polyalkylpiperidine derivatives, the products with blocked end groups thus obtained and their use as light stabilisers for synthetic materials CIBA-GEIGY AG (CH) 1979-05-30 EP disclosed
US-4151356-A STABILIZERS AGAINST OXIDATION AND LIGHT DEGRADATION CIBA-GEIGY CORPORATION (US) 1979-04-24 US disclosed
US-4108829-A PHOTOSTABILITY CHIMOSA CHIMICA ORGANICA S.P.A. (IT) 1978-08-22 US disclosed
US-4028334-A STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1977-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080251758-A1 Triazine Compounds Comprising Substituents Containing Amino Groups and Carboxyl Groups GTF3C5, BAZ2A, AADAC PDE4A 3365/4885ALDH1A1 2004/4885LMNA 4433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.