SCHEMBL460292

SCHEMBL460292

CC(SCC[C]=O)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.36
EPHX1 P07099 1/20 0.33
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9260321 0.81 CYP1A2 (0.33) EPHX1ALDH1A1HSD17B10
SCHEMBL457691 0.77
SCHEMBL5328559 0.75
SCHEMBL7140181 0.75
SCHEMBL2138350 0.74 EPHX1 (0.41) TP53EPHX1ALDH1A1HSD17B10
SCHEMBL2762997 0.73 TSHR (0.48) EPHX1HSD17B10
SCHEMBL11360513 0.73
SCHEMBL10676865 0.73
SCHEMBL8796019 0.73
SCHEMBL3154127 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2614066-B1 PROCESS FOR THE PRODUCTION OF CEPHALOSPORINS DSM SINOCHEM PHARM NL BV (NL) 2017-11-29 EP claimed
EP-2614066-A1 PROCESS FOR THE PRODUCTION OF CEPHALOSPORINS DSM Sinochem Pharmaceuticals Netherlands B.V. (NL) 2013-07-17 EP claimed
WO-2012032040-A1 PROCESS FOR THE PRODUCTION OF CEPHALOSPORINS DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) 2012-03-15 WO claimed
US-6803460-B2 ACIDIFICATION; CARBONATION DSM IP ASSETS B.V. (NL) 2004-10-12 US claimed
US-20030139595-A1 Novel process for the fermentative production of cephalosporin DSM IP ASSETS B.V. (NL) 2003-07-24 US claimed
US-6552185-B1 Acidifying and/or contacting with carbon dioxide followed by adsorption chromatography DSM N.V. (NL) 2003-04-22 US claimed
EP-1066294-B1 NOVEL PROCESS FOR THE FERMENTATIVE PRODUCTION OF CEPHALOSPORIN DSM NV (NL) 2002-10-30 EP claimed
EP-2614066-B1 PROCESS FOR THE PRODUCTION OF CEPHALOSPORINS DSM SINOCHEM PHARM NL BV (NL) 2017-11-29 EP disclosed
EP-2614066-A1 PROCESS FOR THE PRODUCTION OF CEPHALOSPORINS DSM Sinochem Pharmaceuticals Netherlands B.V. (NL) 2013-07-17 EP disclosed
WO-2012032040-A1 PROCESS FOR THE PRODUCTION OF CEPHALOSPORINS DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) 2012-03-15 WO disclosed
US-6803460-B2 ACIDIFICATION; CARBONATION DSM IP ASSETS B.V. (NL) 2004-10-12 US disclosed
CN-1138781-C Novel process for fermentative production of cephalosporin DSM 2004-02-18 CN disclosed
US-20030139595-A1 Novel process for the fermentative production of cephalosporin DSM IP ASSETS B.V. (NL) 2003-07-24 US disclosed
EP-1066294-A1 NOVEL PROCESS FOR THE FERMENTATIVE PRODUCTION OF CEPHALOSPORIN DSM N.V. (NL) 2001-01-10 EP disclosed
EP-1066294-A1 NOVEL PROCESS FOR THE FERMENTATIVE PRODUCTION OF CEPHALOSPORIN DSM N.V. (NL) 2001-01-10 EP disclosed
WO-1999050271-A1 NOVEL PROCESS FOR THE FERMENTATIVE PRODUCTION OF CEPHALOSPORIN DSM N.V. (NL) 1999-10-07 WO disclosed
WO-1999050271-A1 NOVEL PROCESS FOR THE FERMENTATIVE PRODUCTION OF CEPHALOSPORIN DSM N.V. (NL) 1999-10-07 WO disclosed
US-5795733-A Process for the efficient production of 7-ADCA via 3-(carboxyethylthio) propionyl-7-ADCA GIST-BROCADES, B.V. (NL) 1998-08-18 US disclosed
EP-0711348-A1 PROCESS FOR THE EFFICIENT PRODUCTION OF 7-ADCA VIA 3-(CARBOXYETHYLTHIO)PROPIONYL-7-ADCA GIST-BROCADES B.V. (NL) 1996-05-15 EP disclosed
WO-1995004149-A1 PROCESS FOR THE EFFICIENT PRODUCTION OF 7-ADCA VIA 3-(CARBOXYETHYLTHIO)PROPIONYL-7-ADCA GIST-BROCADES B.V. (NL) 1995-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139595-A1 Novel process for the fermentative production of cephalosporin ACSL6, ADSL, COASY TP53 4722/4885EPHX1 3342/4885ALDH1A1 421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.