SCHEMBL4603157

SCHEMBL4603157

[CH2]c1cc(Oc2ccccc2)cc(Oc2ccccc2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.60
TSHR P16473 1/20 0.60
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
NLRP3 Q96P20 1/20 0.52
MAOB P27338 1/20 0.46
NR1H2 P55055 1/20 0.46
BAX Q07812 1/20 0.46
MAOA P21397 1/20 0.46
GSTP1 P09211 1/20 0.43
MITF O75030 1/20 0.43
ALDH1A1 P00352 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
GFER P55789 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NLRP1 Q9C000 1/20 0.43
NOD2 Q9HC29 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10544301 0.89 LTA4H (0.59) LTA4HTSHRMEN1KMT2ANPC1
SCHEMBL6545667 0.87 LTA4H (0.80) LTA4HTSHRMEN1KMT2ANPC1
SCHEMBL11745259 0.87 LTA4H (0.80) LTA4HTSHRMEN1KMT2ANPC1
SCHEMBL10547899 0.85 LTA4H (0.48) LTA4HTSHRMEN1KMT2ANPC1
SCHEMBL10549575 0.85 LTA4H (0.48) LTA4HTSHRMEN1KMT2ANPC1
SCHEMBL10549494 0.85 LTA4H (0.48) LTA4HTSHRMEN1KMT2ANPC1
SCHEMBL5074373 0.84 TSHR (0.43) LTA4HTSHRMEN1KMT2ANPC1
SCHEMBL95809 0.83 LTA4H (0.57) LTA4HTSHRMEN1KMT2ANPC1
SCHEMBL9343331 0.81 LTA4H (0.55) LTA4HTSHRMEN1KMT2AMAOB
Diphenylether SCHEMBL29208899 0.81 LTA4H (0.92) LTA4HTSHRMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1942159-A1 Two-part curable ink composition set and ink jet recording method, ink jet recording apparatus, and printed product using the same SEIKO EPSON CORPORATION (JP) 2008-07-09 EP disclosed
US-5670526-A ANTIINFLAMMATORY AGENT, IMMUNOSUPPRESSANT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-09-23 US disclosed
US-4414210-A 2-Hydroxyarylethyltriazole fungicides ROHM AND HAAS COMPANY (US) 1983-11-08 US disclosed
US-4413003-A FUNGICIDES ROHM AND HAAS COMPANY (US) 1983-11-01 US disclosed