Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 2/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | MLNR | O43193 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459878 | 0.84 | HCAR2 (0.32) | NTRK1JAK2 | |
| SCHEMBL457509 | 0.80 | NTRK1 (0.33) | MEN1KMT2AATMABL1NTRK1 | |
| SCHEMBL457723 | 0.73 | NTRK1 (0.34) | MEN1KMT2AATMNTRK1JAK2 | |
| SCHEMBL459071 | 0.70 | NTRK1 (0.33) | MEN1KMT2ANTRK1 | |
| SCHEMBL18914461 | 0.59 | TP53 (0.39) | KCNH2 | |
| SCHEMBL13858631 | 0.56 | KDM1A (0.44) | NTRK1JAK2KCNH2 | |
| SCHEMBL7887451 | 0.56 | NR1I2 (0.55) | MEN1KMT2AATMKCNH2 | |
| SCHEMBL5680300 | 0.56 | MEN1 (0.39) | MEN1KMT2AATMNTRK1JAK2 | |
| SCHEMBL23327795 | 0.54 | POLQ (0.38) | BACE1ABL1 | |
| SCHEMBL11658820 | 0.54 | RXFP1 (0.37) | MEN1KMT2AATMNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |