Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457509 | 0.89 | NTRK1 (0.33) | HCAR2NTRK1JAK2 | |
| SCHEMBL457441 | 0.88 | — | — | |
| SCHEMBL460321 | 0.84 | BACE1 (0.32) | NTRK1JAK2 | |
| SCHEMBL457723 | 0.77 | NTRK1 (0.34) | NTRK1JAK2 | |
| SCHEMBL459071 | 0.76 | NTRK1 (0.33) | NTRK1 | |
| SCHEMBL13858631 | 0.61 | KDM1A (0.44) | HCAR2NTRK1JAK2HTR2AHTR2C | |
| SCHEMBL1721284 | 0.58 | FPR1 (0.47) | NTRK1JAK2 | |
| SCHEMBL18914461 | 0.57 | TP53 (0.39) | L3MBTL1HTR2AHTR2C | |
| SCHEMBL18914441 | 0.56 | CHRNB2 (0.39) | HTR2AHTR2C | |
| SCHEMBL5899779 | 0.56 | KDM1A (0.44) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |