Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LIPE | Q05469 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749096 | 0.79 | HTT (0.45) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL7747487 | 0.79 | HTT (0.45) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL1259794 | 0.79 | HTT (0.45) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL15282042 | 0.79 | HTT (0.45) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL7749230 | 0.79 | HTT (0.45) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL21798768 | 0.78 | HTT (0.48) | HTTLIPEL3MBTL1LMNAPOLB | |
| Hydrochloric Acid SCHEMBL27317890 | 0.77 | HTT (0.44) | HTTLIPEL3MBTL1LMNAPOLB | |
| Hydrochloric Acid SCHEMBL27543811 | 0.77 | HTT (0.44) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL244127 | 0.76 | — | — | |
| SCHEMBL3158910 | 0.76 | HTT (0.47) | HTTLIPEL3MBTL1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188290-B2 | Reacting secondary amine, carbon dioxide, triarylsilyl chloride and halogenation agent | GLAXO GROUP LIMITED (GB) | 2012-05-29 | — | — | US | disclosed |
| US-20080262234-A1 | Process for Preparing N, N-Substituted Carbamoyl Halides | GLAXO GROUP LIMITED | 2008-10-23 | — | — | US | disclosed |
| EP-1940783-A1 | PROCESS FOR PREPARING N, N-SUBSTITUTED CARBAMOYL HALIDES | GLAXO GROUP LIMITED (GB) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007048642-A1 | PROCESS FOR PREPARING N, N-SUBSTITUTED CARBAMOYL HALIDES | GLAXO GROUP LIMITED (GB) | 2007-05-03 | — | — | WO | disclosed |
| WO-1995021155-A1 | PROCESS FOR PREPARING N,N-SUBSTITUTED CARBAMOYL HALIDES FROM SECONDARY AMINES, CARBON DIOXIDE AND HALIDE-CONTAINING ELECTROPHILIC COMPOUNDS | MONSANTO COMPANY (US) | 1995-08-10 | — | — | WO | disclosed |
| US-5380855-A | Carbon dioxide and secondary amine | MONSANTO COMPANY (US) | 1995-01-10 | — | — | US | disclosed |