Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4605460 | 1.00 | TSHR (0.65) | TSHRHSD17B10GPR3PSMB5RARB | |
| SCHEMBL11572123 | 1.00 | TSHR (0.65) | TSHRHSD17B10GPR3PSMB5RARB | |
| SCHEMBL11730491 | 1.00 | TSHR (0.65) | TSHRHSD17B10GPR3PSMB5RARB | |
| SCHEMBL9632643 | 1.00 | TSHR (0.65) | TSHRHSD17B10GPR3PSMB5RARB | |
| SCHEMBL4651878 | 0.99 | TSHR (0.62) | TSHRHSD17B10GPR3PSMB5RARB | |
| SCHEMBL4604750 | 0.99 | TSHR (0.62) | TSHRHSD17B10GPR3PSMB5RARB | |
| SCHEMBL30266947 | 0.99 | TSHR (0.62) | TSHRHSD17B10GPR3PSMB5RARB | |
| SCHEMBL10606870 | 0.92 | TSHR (0.65) | TSHRHSD17B10GPR3RARBHSD11B1 | |
| SCHEMBL11339892 | 0.92 | TSHR (0.65) | TSHRHSD17B10GPR3RARBHSD11B1 | |
| SCHEMBL8621174 | 0.92 | TSHR (0.65) | TSHRHSD17B10GPR3RARBHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680482-B1 | SILICONE COMPOSITION AND POLYMER DISPERSED LIQUID CRYSTAL | DOW CORNING (US) | 2008-10-08 | — | — | EP | disclosed |
| EP-1682632-B1 | SILICONE COMPOSITION AND POLYMER DISPERSED LIQUID CRYSTAL | DOW CORNING (US) | 2008-07-09 | — | — | EP | disclosed |
| US-20070003702-A1 | Method of preparing a metal-silicone rubber composite | DOW CORNING CORPORATION | 2007-01-04 | — | — | US | disclosed |
| EP-1689906-A1 | METHOD OF PREPARING A METAL-SILICONE RUBBER COMPOSITE | Dow Corning Corporation (US) | 2006-08-16 | — | — | EP | disclosed |
| EP-1682632-A1 | SILICONE COMPOSITION AND POLYMER DISPERSED LIQUID CRYSTAL | Dow Corning Corporation (US) | 2006-07-26 | — | — | EP | disclosed |
| EP-1680482-A1 | SILICONE COMPOSITION AND POLYMER DISPERSED LIQUID CRYSTAL | Dow Corning Corporation (US) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005056871-A1 | METHOD OF PREPARING A METAL-SILICONE RUBBER COMPOSITE | DOW CORNING CORPORATION (US) | 2005-06-23 | — | — | WO | disclosed |
| WO-2005044949-A1 | SILICONE COMPOSITION AND POLYMER DISPERSED LIQUID CRYSTAL | DOW CORNING CORPORATION (US) | 2005-05-19 | — | — | WO | disclosed |
| WO-2005044950-A1 | SILICONE COMPOSITION AND POLYMER DISPERSED LIQUID CRYSTAL | DOW CORNING CORPORATION (US) | 2005-05-19 | — | — | WO | disclosed |