Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.68 |
| ▸ | KDR | P35968 | 20/20 | 0.68 |
| ▸ | MST1R | Q04912 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306357 | 0.92 | MET (0.80) | METKDRMST1R | |
| SCHEMBL307088 | 0.85 | MET (0.89) | METKDRMST1R | |
| SCHEMBL307151 | 0.84 | MET (0.81) | METKDRMST1R | |
| SCHEMBL10254768 | 0.84 | MET (0.76) | METKDRMST1R | |
| SCHEMBL307197 | 0.82 | MET (0.68) | METKDRMST1R | |
| SCHEMBL307926 | 0.82 | MET (0.80) | METKDRMST1R | |
| SCHEMBL306356 | 0.81 | MET (0.79) | METKDRMST1R | |
| SCHEMBL306290 | 0.81 | MET (1.00) | METKDRMST1R | |
| SCHEMBL4602255 | 0.80 | MET (0.59) | METKDRMST1R | |
| SCHEMBL14230562 | 0.80 | MET (0.74) | METKDRMST1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957498-A2 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | MethylGene Inc. (CA) | 2008-08-20 | — | — | EP | claimed |
| WO-2008041053-A2 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | METHYLGENE, INC. (CA) | 2008-04-10 | — | — | WO | claimed |
| EP-1957498-A2 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | MethylGene Inc. (CA) | 2008-08-20 | — | — | EP | disclosed |
| WO-2008041053-A2 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | METHYLGENE, INC. (CA) | 2008-04-10 | — | — | WO | disclosed |