Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 16/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 15/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435738 | 1.00 | ALOX5 (0.42) | ALOX5CYP11B1CYP11B2 | |
| SCHEMBL2109199 | 1.00 | ALOX5 (0.42) | ALOX5CYP11B1CYP11B2 | |
| SCHEMBL9435741 | 1.00 | ALOX5 (0.42) | ALOX5CYP11B1CYP11B2 | |
| SCHEMBL8551667 | 0.93 | ALOX5 (0.37) | ALOX5CYP11B1 | |
| SCHEMBL2108142 | 0.86 | ALOX5 (0.51) | ALOX5CYP11B1CYP11B2 | |
| SCHEMBL8554174 | 0.82 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL8552719 | 0.82 | ALOX5 (0.38) | ALOX5 | |
| SCHEMBL2108127 | 0.81 | ALOX5 (0.39) | ALOX5CYP11B1CYP11B2 | |
| SCHEMBL8979505 | 0.79 | ALOX5 (0.50) | ALOX5CYP11B1CYP11B2 | |
| SCHEMBL2109679 | 0.78 | ALOX5 (0.37) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871908-A2 | SUSCEPTIBILITY GENE FOR MYOCARDIAL INFARCTION, STROKE AND PAOD; METHODS OF TREATMENT | Decode Genetics EHF. (IS) | 2008-01-02 | — | — | EP | disclosed |
| EP-1718284-A2 | SUSCEPTIBILITY GENE FOR MYOCARDIAL INFRACTION, STROKE, AND PAOD; METHODS OF TREATMENT | Decode Genetics EHF. (IS) | 2006-11-08 | — | — | EP | disclosed |
| WO-2006105439-A2 | SUSCEPTIBILITY GENE FOR MYOCARDIAL INFARCTION, STROKE. AND PAOD; METHODS OF TREATMENT | DECODE GENETICS EHF. (IS) | 2006-10-05 | — | — | WO | disclosed |
| WO-2005075022-A2 | SUSCEPTIBILITY GENE FOR MYOCARDIAL INFRACTION, STROKE, AND PAOD; METHODS OF TREATMENT | DECODE GENETICS EHF. (IS) | 2005-08-18 | — | — | WO | disclosed |
| WO-1994025453-A1 | 4-ARYL-4-HYDROXY-TETRAHYDROPYRANS AND 3-ARYL-3-HYDROXY-TETRAHYDROFURANS AS 5-LIPOXYGENASE INHIBITORS | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |