Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 19/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 19/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 18/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289929 | 0.92 | TAS1R3 (0.47) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4247030 | 0.84 | TAS1R3 (0.58) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4246193 | 0.84 | TAS1R3 (0.58) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4246190 | 0.84 | TAS1R3 (0.58) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2295312 | 0.82 | TAS1R3 (0.47) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4242205 | 0.82 | TAS1R3 (0.55) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4247481 | 0.81 | TAS1R3 (0.52) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4603970 | 0.80 | SCN9A (0.33) | — | |
| SCHEMBL2285724 | 0.80 | TAS1R3 (0.52) | TAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL13013798 | 0.80 | TAS1R3 (0.45) | TAS1R3TAS1R1TAS1R2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940780-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049728-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |