Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.52 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961004 | 0.95 | GABRA1 (0.50) | GABRA1GABRB2PDCD1CD274CYP4F2 | |
| SCHEMBL17417172 | 0.91 | GABRA1 (0.52) | GABRA1GABRB2PDCD1CD274TAAR1 | |
| SCHEMBL245773 | 0.87 | GABRA1 (0.57) | GABRA1GABRB2TAAR1HTR1AKCNH2 | |
| SCHEMBL320050 | 0.85 | GABRA1 (0.56) | GABRA1GABRB2PDCD1CD274TAAR1 | |
| SCHEMBL7643320 | 0.85 | GABRA1 (0.39) | GABRA1GABRB2PDCD1CD274CYP4F2 | |
| Methane SCHEMBL28776675 | 0.85 | GABRA1 (0.55) | GABRA1GABRB2TAAR1HTR1AKCNH2 | |
| Ammonia Solution, Strong SCHEMBL27320869 | 0.85 | GABRA1 (0.55) | GABRA1GABRB2TAAR1HTR1AKCNH2 | |
| SCHEMBL31498538 | 0.85 | GABRA1 (0.55) | GABRA1GABRB2TAAR1HTR1AKCNH2 | |
| Methylamine SCHEMBL27545014 | 0.85 | GABRA1 (0.55) | GABRA1GABRB2TAAR1HTR1AALDH1A1 | |
| SCHEMBL3811653 | 0.85 | GABRA1 (0.41) | GABRA1GABRB2PDCD1CD274CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053709-A1 | PROCESS FOR THE PREPARATION OF MEDETOMIDINE | NORBROOK LABORATORIES LIMITED (GB) | 2009-04-30 | — | — | WO | claimed |
| CN-107709224-A | The silane-modified fluid reduced for MEMS static friction | 追踪有限公司 | 2018-02-16 | — | — | CN | disclosed |
| CN-106905462-A | A kind of dispersant and preparation method thereof | 淄博职业学院 | 2017-06-30 | — | — | CN | disclosed |
| US-9540331-B2 | Preparation method of dexmedetomidine intermediate | TIANJIN WEIJIE PHARMACEUTICAL CO., LTD (CN) | 2017-01-10 | — | — | US | disclosed |
| US-20160272594-A1 | PREPARATION METHOD OF DEXMEDETOMIDINE INTERMEDIATE | TIANJIN WEIJIE PHARMACEUTICAL CO., LTD (CN) | 2016-09-22 | — | — | US | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| US-8809462-B2 | Ethylene-α-olefin copolymer, molded article, catalyst for copolymerization, and method for producing an ethylene-α-olefin copolymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-19 | — | — | US | disclosed |
| CN-101291901-B | Polyvinyl ether compound | IDEMITSU KOSAN CO | 2013-03-13 | — | — | CN | disclosed |
| US-20120065351-A1 | ETHYLENE-ALPHA-OLEFIN COPOLYMER AND MOLDED ARTICLE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
| US-20120065346-A1 | ETHYLENE-ALPHA-OLEFIN COPOLYMER, MOLDED ARTICLE, CATALYST FOR COPOLYMERIZATION, AND METHOD FOR PRODUCING AN ETHYLENE-ALPHA-OLEFIN COPOLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
| CN-1088050-C | Alkylation process using zeolite beta | EXXON MOBILE CHEMICAL PATENTS (US) | 2002-07-24 | — | — | CN | disclosed |
| CN-1239471-A | Alkylation process using zeolite beta | EXXON CHEMICAL PATENTS INC (US) | 1999-12-22 | — | — | CN | disclosed |
| US-5149884-A | Oxidative dehydrogenation of aromatic or aliphatic alcohols in gas phase | BASF AKTIENGESELLSCHAFT (DE) | 1992-09-22 | — | — | US | disclosed |
| EP-0244632-B1 | TUBE BUNDLE REACTOR, ITS USE IN EXOTHERMAL ORGANIC REACTIONS AND PROCESS FOR THE PREPARATION OF KETONES AND ALDEHYDES | BASF Aktiengesellschaft (DE) | 1991-02-20 | — | — | EP | disclosed |
| EP-0245854-B1 | PROCESS FOR PRODUCING OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-09-20 | — | — | EP | disclosed |
| US-4806433-A | ORGANOTITANIUM, ALUMINUM, MAGNESIUM COMPONENTS FOR COORDINATION CATALYSTS; ETHER, ESTER TREATMENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-02-21 | — | — | US | disclosed |
| EP-0245854-A1 | Process for producing olefin polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-11-19 | — | — | EP | disclosed |
| EP-0244632-A2 | Tube bundle reactor, its use in exothermal organic reactions and process for the preparation of ketones and aldehydes | BASF Aktiengesellschaft (DE) | 1987-11-11 | — | — | EP | disclosed |
| US-4306083-A | Multiphase oxidation of alcohol to aldehyde | THE DOW CHEMICAL COMPANY (US) | 1981-12-15 | — | — | US | disclosed |
| US-4224254-A | OXIDATION OF AROMATIC ALCOHOLS, SILVER CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1980-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272594-A1 | PREPARATION METHOD OF DEXMEDETOMIDINE INTERMEDIATE | AVPR2, TET1, TET2 | GABRA1 486/4885GABRB2 279/4885PDCD1 1963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.