Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.54 |
| ▸ | CA2 | P00918 | 11/20 | 0.54 |
| ▸ | CA12 | O43570 | 9/20 | 0.54 |
| ▸ | CA9 | Q16790 | 8/20 | 0.54 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | VEGFA | P15692 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604803 | 0.89 | CA1 (0.53) | CA1CA2CA12CA9CA7 | |
| SCHEMBL4604312 | 0.89 | CA1 (0.54) | CA1CA2CA12CA9CA7 | |
| SCHEMBL2640174 | 0.86 | CA1 (0.54) | CA1CA2CA12CA9CA7 | |
| SCHEMBL2638940 | 0.84 | CA1 (0.54) | CA1CA2CA12CA9CA7 | |
| SCHEMBL4604671 | 0.84 | CA1 (0.53) | CA1CA2CA12CA9CA7 | |
| SCHEMBL4602886 | 0.83 | CA1 (0.53) | CA1CA2CA12CA9CA7 | |
| SCHEMBL2638407 | 0.82 | CA1 (0.53) | CA1CA2CA12CA9CA7 | |
| SCHEMBL2639938 | 0.82 | CA1 (0.53) | CA1CA2CA12CA9CA7 | |
| SCHEMBL4602268 | 0.82 | CA1 (0.53) | CA1CA2CA12CA9CA7 | |
| SCHEMBL2638534 | 0.82 | CA2 (0.51) | CA1CA2CA12CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940781-A1 | PHENYL-ACETAMIDE NNRT INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-07-09 | — | — | EP | claimed |
| WO-2007045573-A1 | PHENYL-ACETAMIDE NNRT INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-04-26 | — | — | WO | claimed |