⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL636641 | 1.00 | — | — | |
| SCHEMBL638004 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL385419 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL31008508 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL6044576 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL385418 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL30958967 | 0.97 | GABRP (0.40) | — | |
| SCHEMBL12132306 | 0.78 | GABRP (0.36) | — | |
| SCHEMBL10140608 | 0.78 | GABRP (0.36) | — | |
| SCHEMBL13050663 | 0.78 | GABRP (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119432794-A | Process for preparing (S) -3-aminobutyric acid by transaminase catalysis | 宁波酶赛生物工程有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-119431184-A | Synthesis method of (S) -3-aminobutyric acid | 宁波酶赛生物工程有限公司 | 2025-02-14 | — | — | CN | claimed |
| US-12473295-B2 | Substituted straight chain spiro derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2025-11-18 | — | — | US | disclosed |
| CN-119431184-A | Synthesis method of (S) -3-aminobutyric acid | 宁波酶赛生物工程有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-119431184-A | Synthesis method of (S) -3-aminobutyric acid | 宁波酶赛生物工程有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-119432794-A | Process for preparing (S) -3-aminobutyric acid by transaminase catalysis | 宁波酶赛生物工程有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-119432794-A | Process for preparing (S) -3-aminobutyric acid by transaminase catalysis | 宁波酶赛生物工程有限公司 | 2025-02-14 | — | — | CN | disclosed |
| US-20230142285-A1 | SUBSTITUTED STRAIGHT CHAIN SPIRO DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2023-05-11 | — | — | US | disclosed |
| CN-111848483-B | Asymmetric catalytic preparation method of brivaracetam | 南方科技大学 | 2022-09-23 | — | — | CN | disclosed |
| EP-3177616-B1 | NOVEL ROUTES OF SYNTHESIS FOR THE PREPARATION OF SUVOREXANT | SANDOZ AG (CH) | 2021-02-24 | — | — | EP | disclosed |
| CN-111848483-A | Asymmetric catalytic preparation method of brivaracetam | 南方科技大学 | 2020-10-30 | — | — | CN | disclosed |
| EP-3041468-B1 | CYCLIC PEPTIDOMIMETIC COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2018-06-13 | — | — | EP | disclosed |
| EP-2809655-B1 | BENZIIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AS SODIUM CHANNEL MODULATORS | PFIZER (US) | 2015-08-12 | — | — | EP | disclosed |
| US-8927587-B2 | Chemical compounds | PFIZER LIMITED (GB) | 2015-01-06 | — | — | US | disclosed |
| US-20130274243-A1 | Chemical Compounds | PFIZER LTD (GB) | 2013-10-17 | — | — | US | disclosed |
| US-7456194-B2 | Imidazo-fused oxazolo [4,5-b]pyridine and imidazo-fused thiazolo[4,5-b]pyridine based tricyclic compounds and pharmaceutical compositions comprising same | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-25 | — | — | US | disclosed |
| EP-1768978-B1 | 2,4,6-TRISUBSTITUTED PYRIMIDINES AS PHOSPHOTIDYLINOSITOL (PI) 3-KINASE INHIBITORS AND THEIR USE IN THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2008-07-09 | — | — | EP | disclosed |
| US-20080058332-A1 | 2,4,6-Trisubstituted Pyrimidines as Phosphotidylinositol (Pi) 3-Kinase Inhibitors and Their Use in the Treatment of Cancer | ASTRAZENECA AB (SE) | 2008-03-06 | — | — | US | disclosed |