Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 8/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604670 | 0.97 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL4605459 | 0.97 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL4605029 | 0.91 | TSHR (0.58) | ALDH1A1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL4606124 | 0.90 | TSHR (0.59) | ALDH1A1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL4604586 | 0.88 | TSHR (0.58) | ALDH1A1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL4603546 | 0.88 | TSHR (0.58) | ALDH1A1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL4603600 | 0.88 | TSHR (0.53) | ALDH1A1TSHRTDP1L3MBTL1TP53 | |
| SCHEMBL4605747 | 0.87 | TSHR (0.59) | ALDH1A1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL4604221 | 0.87 | TSHR (0.59) | ALDH1A1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL28103147 | 0.86 | TSHR (0.60) | ALDH1A1TSHRTDP1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139710-B2 | Aliphatic polyester resin compositions, molded articles of aliphatic polyester resin and method of producing same | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 2015-09-22 | — | — | US | disclosed |
| EP-1707598-B1 | ALIPHATIC POLYESTER RESIN COMPOSITION, ALIPHATIC POLYESTER RESIN MOLDING AND PROCESS FOR PRODUCING THE ALIPHATIC POLYESTER RESIN MOLDING | TAKEMOTO OIL & FAT CO LTD (JP) | 2008-07-09 | — | — | EP | disclosed |
| US-20070270535-A1 | Aliphatic Polyester Resin Compositions, Molded Articles of Aliphatic Polyester Resin and Method of Producing Same | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 2007-11-22 | — | — | US | disclosed |
| EP-1707598-A1 | ALIPHATIC POLYESTER RESIN COMPOSITION, ALIPHATIC POLYESTER RESIN MOLDING AND PROCESS FOR PRODUCING THE ALIPHATIC POLYESTER RESIN MOLDING | Takemoto Yushi Kabushiki Kaisha (JP) | 2006-10-04 | — | — | EP | disclosed |