SCHEMBL4604222

SCHEMBL4604222

O=C(O)c1ccccc1OS

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.59
ALDH1A1 P00352 9/20 0.59
HSD17B10 Q99714 6/20 0.59
HPGD P15428 6/20 0.59
HMGB1 P09429 2/20 0.59
NAPRT Q6XQN6 2/20 0.59
ESR1 P03372 1/20 0.59
ITGB3 P05106 1/20 0.59
ITGA2B P08514 1/20 0.59
TSHR P16473 1/20 0.59
GGT1 P19440 1/20 0.59
PTGS1 P23219 1/20 0.59
PTGS2 P35354 1/20 0.59
BLM P54132 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
MAPT P10636 2/20 0.57
USP2 O75604 1/20 0.57
PDE3A Q14432 1/20 0.57
ALOX15 P16050 1/20 0.56
HTT P42858 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL104479 0.82 KDM4E (0.59) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL29352508 0.82 KDM4E (0.59) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL446113 0.81 HTT (0.77) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL29682980 0.81 HTT (0.77) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL29010714 0.81 KDM4E (0.63) KDM4EALDH1A1HSD17B10HPGDHMGB1
Hydrazine SCHEMBL4457442 0.80 KDM4E (0.57) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL27946346 0.80 KDM4E (0.57) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL27521082 0.80 KDM4E (0.57) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL9457629 0.80 CTNNB1 (0.60) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL8434168 0.79 HTT (0.81) KDM4EALDH1A1HSD17B10HPGDHMGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117659226-A Chitosan containing sulfhydryl group and preparation method and application thereof 中国科学院烟台海岸带研究所 2024-03-08 CN claimed
CN-115073435-B Near infrared fluorescent probe for detecting hydrogen sulfide and preparation method thereof 西北大学 2023-11-28 CN claimed
CN-115073435-A Near-infrared fluorescent probe for detecting hydrogen sulfide and preparation method thereof 西北大学 2022-09-20 CN claimed
CN-109096357-B Synthesis and application of naphthalene imide derivative containing thioether and cholesterol ester 大连理工大学 2020-07-14 CN claimed
US-7470451-B2 Binding agent component for surface coating agents with improved adhesive properties HENKEL AG & CO. KGAA (DE) 2008-12-30 US claimed
EP-0402751-B1 Derivatives of salicylic aldehyde and salicylic acid and sulphur analoges thereof, methodes for preparing them and their use as herbicides and bioregulators BASF AG (DE) 1994-05-04 EP claimed
CN-114725324-B Preparation and application of zinc metal anode integrated by coordination supermolecular grid material 中山大学 2024-04-30 CN disclosed
CN-117659226-A Chitosan containing sulfhydryl group and preparation method and application thereof 中国科学院烟台海岸带研究所 2024-03-08 CN disclosed
CN-116874641-B Chitosan hydrochloride containing sulfhydryl acid salt and preparation method and application thereof 中国科学院烟台海岸带研究所 2023-12-01 CN disclosed
CN-115073435-B Near infrared fluorescent probe for detecting hydrogen sulfide and preparation method thereof 西北大学 2023-11-28 CN disclosed
CN-115073435-B Near infrared fluorescent probe for detecting hydrogen sulfide and preparation method thereof 西北大学 2023-11-28 CN disclosed
CN-116874641-A Chitosan hydrochloride containing sulfhydryl acid salt and preparation method and application thereof 中国科学院烟台海岸带研究所 2023-10-13 CN disclosed
US-20220396881-A1 METHOD FOR FABRICATING ELECTRONIC COMPONENT C. UYEMURA & CO., LTD. (JP) 2022-12-15 US disclosed
WO-2005054225-A1 ANTIDIABETIC COMPOUNDS COMPRISING BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES MERCK PATENT GMBH (DE) 2005-06-16 WO disclosed
WO-2005054226-A1 BENZOFURANS AND BENZOTHIOPHENES MERCK PATENT GMBH (DE) 2005-06-16 WO disclosed
US-20050129955-A1 Binding agent component for surface coating agents with improved adhesive properties HENKEL AG & CO. KGAA (DE) 2005-06-16 US disclosed
EP-1098912-B1 INHIBITING SCALE IN VINYL MONOMER POLYMERIZATION OXY VINYLS LP (US) 2004-03-10 EP disclosed
US-6300427-B1 USED TO PREVENT FORMATION OF SCALE ON REACTOR SURFACES OCCIDENTAL CHEMICAL CORPORATION 2001-10-09 US disclosed
US-6114476-A CONTACTING MONOMER WITH TERPOLYMER WHICH COMPRISES THE CONDENSATION REACTION PRODUCT OF AN AROMATIC COMPOUND, A CARBONYL COMPOUND, AND A THIOUREA OCCIDENTAL CHEMICAL CORPORATION (US) 2000-09-05 US disclosed
US-4730053-A DISEASES, CELL INJURIES, METABOLITES A. NATTERMANN & CIE GMBH (DE) 1988-03-08 US disclosed