Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | PTAFR | P25105 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24973095 | 0.84 | KMT2A (0.41) | MEN1LMNAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL15121087 | 0.80 | KMT2A (0.43) | MEN1LMNAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL2757254 | 0.77 | LMNA (0.46) | MEN1LMNAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL4440798 | 0.76 | TAAR1 (0.41) | TRPA1 | |
| SCHEMBL958610 | 0.74 | SMN1; SMN2 (0.50) | MEN1LMNAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL12197959 | 0.74 | MEN1 (0.44) | MEN1LMNAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL4353619 | 0.74 | TSHR (0.53) | MEN1LMNAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL29450849 | 0.74 | TSHR (0.53) | MEN1LMNAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL132853 | 0.73 | — | — | |
| SCHEMBL29450844 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915338-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007017754-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2007-02-15 | — | — | WO | disclosed |