SCHEMBL4604548

SCHEMBL4604548

CCO[Si](OCC)(OCC)C(C)CC1CC2C=CC1C2

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 2/20 0.40
IDO1 P14902 1/20 0.32
TDO2 P48775 1/20 0.32
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203038 0.84 KDM4E (0.38) KDM4EALDH1A1IDO1TDO2MEN1
SCHEMBL465320 0.75 KDM4E (0.47) KDM4EALDH1A1IDO1TDO2MEN1
SCHEMBL6063839 0.75 KDM4E (0.40) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL6064103 0.75 KDM4E (0.40) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL6064357 0.74 KDM4E (0.41) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL200330 0.74 KDM4E (0.32) KDM4EALDH1A1
SCHEMBL1878286 0.73 KDM4E (0.44) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL28826468 0.73 KDM4E (0.46) KDM4EALDH1A1IDO1TDO2MEN1
SCHEMBL6063995 0.73 ALDH1A1 (0.38) KDM4EALDH1A1MEN1KMT2A
SCHEMBL6063040 0.73 ALDH1A1 (0.38) KDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1364975-B1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR CORP (JP) 2008-04-30 EP disclosed
US-20070225461-A1 Olefin polymers for imaging members LEXMARK INTERNATIONAL INC. 2007-09-27 US disclosed
US-20070112158-A1 Novel (co)polymer, process for producing the same, and process for producing carboxylated (co)polymer JSR CORPORATION (JP) 2007-05-17 US disclosed
EP-1686139-A1 NOVEL (CO)POLYMER, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING CARBOXYLATED (CO)POLYMER JSR Corporation (JP) 2006-08-02 EP disclosed
US-6911507-B2 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2005-06-28 US disclosed
US-20040063873-A1 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2004-04-01 US disclosed
EP-1364975-A1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR Corporation (JP) 2003-11-26 EP disclosed