Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4587920 | 0.91 | CCR5 (0.64) | CCR5 | |
| SCHEMBL4605196 | 0.88 | CCR5 (0.74) | CCR5 | |
| SCHEMBL4586987 | 0.88 | CCR5 (0.62) | CCR5 | |
| SCHEMBL13931476 | 0.86 | CCR5 (0.68) | CCR5 | |
| SCHEMBL4243323 | 0.83 | CCR5 (0.61) | CCR5 | |
| SCHEMBL4239869 | 0.82 | CCR5 (0.63) | CCR5 | |
| SCHEMBL4586601 | 0.81 | CCR5 (0.58) | CCR5 | |
| SCHEMBL4244479 | 0.80 | CCR5 (0.57) | CCR5 | |
| SCHEMBL4603239 | 0.80 | CCR5 (0.58) | CCR5 | |
| SCHEMBL4586581 | 0.78 | CCR5 (0.52) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708703-A4 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2008-04-09 | — | — | EP | disclosed |
| EP-1708703-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005059107-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2005-06-30 | — | — | WO | disclosed |