Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13295556 | 1.00 | LMNA (0.56) | LMNAGPR84FFAR1FFAR4SPHK1 | |
| SCHEMBL28684984 | 1.00 | LMNA (0.56) | LMNAGPR84FFAR1FFAR4SPHK1 | |
| SCHEMBL27970623 | 1.00 | LMNA (0.56) | LMNAGPR84FFAR1FFAR4SPHK1 | |
| SCHEMBL27612144 | 1.00 | LMNA (0.56) | LMNAGPR84FFAR1FFAR4SPHK1 | |
| SCHEMBL10426629 | 1.00 | LMNA (0.56) | LMNAGPR84FFAR1FFAR4SPHK1 | |
| SCHEMBL28505941 | 1.00 | LMNA (0.56) | LMNAGPR84FFAR1FFAR4SPHK1 | |
| SCHEMBL28905358 | 1.00 | LMNA (0.56) | LMNAGPR84FFAR1FFAR4SPHK1 | |
| SCHEMBL31624676 | 0.98 | LMNA (0.54) | LMNAGPR84FFAR1FFAR4SPHK1 | |
| SCHEMBL16418383 | 0.93 | LMNA (0.58) | LMNAGPR84FFAR1FFAR4SPHK1 | |
| SCHEMBL5494936 | 0.92 | LMNA (0.54) | LMNAGPR84FFAR1FFAR4SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276553-B2 | DISPERSANTS | LUBRIZOL CORP (US) | 2012-11-07 | — | — | EP | disclosed |
| EP-1276553-B1 | DISPERSANTS | LUBRIZOL CORP (US) | 2008-07-09 | — | — | EP | disclosed |
| US-7348367-B2 | Dispersants | THE LUBRIZOL CORPORATION (US) | 2008-03-25 | — | — | US | disclosed |
| EP-1702672-A1 | Dispersants | The Lubrizol Corporation (US) | 2006-09-20 | — | — | EP | disclosed |
| EP-1276553-A2 | DISPERSANTS | Avecia Limited (GB) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001080987-A2 | DISPERSANTS | AVECIA LIMITED (GB) | 2001-11-01 | — | — | WO | disclosed |