SCHEMBL460474

SCHEMBL460474

C=CC(=O)OC(=O)/C=C\C(=O)OC(=O)C=C

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 10/20 0.40
ALDH1A1 P00352 8/20 0.40
TP53 P04637 3/20 0.40
HIF1A Q16665 3/20 0.40
CYP3A4 P08684 2/20 0.40
HSD17B10 Q99714 1/20 0.40
HCAR2 Q8TDS4 2/20 0.38
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
LMNA P02545 1/20 0.37
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HPGD P15428 1/20 0.36
FGFR4 P22455 1/20 0.35
MAPT P10636 1/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8817936 1.00 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1502682 1.00 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28795811 0.97 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2425696 0.97 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL278164 0.90
SCHEMBL1789504 0.89 HCAR2 (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL725566 0.89 HCAR2 (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL460475 0.89 HCAR2 (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL30757889 0.87 HCAR2 (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
Ethylene SCHEMBL28659581 0.87 HCAR2 (0.46) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1035 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117980424-A Slurry composition for metal polishing 凯斯科技股份有限公司 2024-05-03 CN claimed
US-20240115485-A1 NAIL COMPOSITION CONTAINING DISPERSION OF ACRYLIC POLYMER PARTICLES L'OREAL (FR) 2024-04-11 US claimed
WO-2024077139-A1 NAIL COMPOSITION CONTAINING DISPERSION OF ACRYLIC POLYMER PARTICLES L'OREAL (FR) 2024-04-11 WO claimed
CN-113257990-B Base metal inner electrode material for multilayer piezoelectric ceramic actuator and preparation method thereof 苏州攀特电陶科技股份有限公司 2024-02-09 CN claimed
US-11771629-B2 Process for the elongation and/or densification of fibers L'OREAL (FR) 2023-10-03 US claimed
CN-115992031-A Post-chemical mechanical polishing cleaning liquid composition 爱思开海力士有限公司 2023-04-21 CN claimed
US-20230057467-A1 COMPOSITION COMPRISING A DISPERSION OF POLYMER PARTICLES IN A NON-AQUEOUS MEDIUM, A CATIONIC POLYMER AND AN ANIONIC POLYMER L'OREAL (FR) 2023-02-23 US claimed
CN-110494121-B Method for dyeing hair using pigment, maleic anhydride acrylic polymer and amine compound 莱雅公司 2022-08-05 CN claimed
EP-3474810-B1 PROCESS FOR THE ELONGATION AND/OR DENSIFICATION OF FIBERS OREAL (FR) 2022-05-11 EP claimed
CN-108366929-B Cosmetic process for treating keratin materials with maleic anhydride ethylenic polymers 莱雅公司 2022-03-25 CN claimed
CN-1137471-A Packaging based on polymer containing polyamide blocks and polyether blocks, for conserving fresh produce ATOCHEM ELF SA (FR) 1996-12-11 CN claimed
US-5545344-A PHOSPHATE-FREE; CONTAINS AT LEAST ONE PROTEASE ENZYME AND AN AMYLASE ENZYME COLGATE-PALMOLIVE CO. (US) 1996-08-13 US claimed
EP-0436514-B1 Polymer compositions and absorbent fibers produced therefrom CAMELOT SUPERABSORBENTS LTD (CA) 1996-07-31 EP claimed
US-5510048-A ETHOXYLATED FATTY ALCOHOL NONIONIC SURFACTANT, POLYETHYLENE GLYCOL CARRIER, ALKALI METAL CARBONATE, ANTIFOAMING AGENT, PROTEASE AND AMYLASE ENZYMES, SODIUM DISILICATE, FINELY DIVIDED FUMED SILICA, NONCROSSLINKED ACRYLATE POLYMER COLGATE PALMOLIVE CO. (US) 1996-04-23 US claimed
US-5151465-A Polymers containing carboxy groups and reactive amine containing compounds ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1992-09-29 US claimed
EP-0436514-A2 Polymer compositions and absorbent fibers produced therefrom CAMELOT SUPERABSORBENTS LTD (CA) 1991-07-10 EP claimed
US-5010134-A Heat resistance, mechanical properties NATIONAL SCIENCE COUNCIL (TW) 1991-04-23 US claimed
EP-0073890-B1 AN ANAEROBIC COMPOSITION, A REACTIVE THICKENER CONTAINED THEREIN AND USE OF THE COMPOSITION AS ADHESIVE OR SEALANT National Starch and Chemical Corporation (US) 1986-04-02 EP claimed
US-4401793-A Polymeric adducts with pendant polymerizable double bonds, their preparation and use as reactive thickeners in improved anaerobic compositions NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1983-08-30 US claimed
EP-0073890-A1 An anaerobic composition, a reactive thickener contained therein and use of the composition as adhesive or sealant National Starch and Chemical Corporation (US) 1983-03-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230057467-A1 COMPOSITION COMPRISING A DISPERSION OF POLYMER PARTICLES IN A NON-AQUEOUS MEDIUM, A CATIONIC POLYMER AND AN ANIONIC POLYMER KRT18, PRKDC, POLR1C TSHR 3309/4885ALDH1A1 4367/4885TP53 856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.