Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604842 | 1.00 | MAPT (0.39) | MAPTALDH1A1KDM4EHPGDCACNA1B | |
| Hydrochloric Acid SCHEMBL3292057 | 0.97 | MAPT (0.39) | MAPTALDH1A1KDM4EHPGDCACNA1B | |
| Hydrochloric Acid SCHEMBL3292054 | 0.97 | MAPT (0.39) | MAPTALDH1A1KDM4EHPGDCACNA1B | |
| SCHEMBL3165623 | 0.88 | ALDH1A1 (0.49) | MAPTALDH1A1KDM4EMRGPRX4MEN1 | |
| SCHEMBL3165619 | 0.88 | ALDH1A1 (0.49) | MAPTALDH1A1KDM4EMRGPRX4MEN1 | |
| SCHEMBL1164472 | 0.86 | MAPT (0.46) | MAPTALDH1A1KDM4ENPSR1MRGPRX4 | |
| SCHEMBL1164471 | 0.86 | MAPT (0.46) | MAPTALDH1A1KDM4ENPSR1MRGPRX4 | |
| Hydrochloric Acid SCHEMBL3174481 | 0.85 | ALDH1A1 (0.47) | MAPTALDH1A1KDM4ENPSR1MRGPRX4 | |
| Bromide SCHEMBL3185901 | 0.85 | ALDH1A1 (0.47) | MAPTALDH1A1KDM4EMRGPRX4MEN1 | |
| SCHEMBL28374528 | 0.84 | MAPT (0.45) | MAPTALDH1A1KDM4ENPSR1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943281-A1 | HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE | Basell Polyolefine GmbH (DE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007042252-A1 | HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE | BASELL POLYOLEFINE GMBH (DE) | 2007-04-19 | — | — | WO | disclosed |