Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 2/20 | 1.00 |
| ▸ | ITGB7 | P26010 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 16/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 16/20 | 0.79 |
| ▸ | POLB | P06746 | 12/20 | 0.79 |
| ▸ | BLM | P54132 | 7/20 | 0.79 |
| ▸ | USP2 | O75604 | 3/20 | 0.79 |
| ▸ | GAA | P10253 | 3/20 | 0.79 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.79 |
| ▸ | RECQL | P46063 | 8/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.73 |
| ▸ | MITF | O75030 | 5/20 | 0.73 |
| ▸ | PKM | P14618 | 4/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.73 |
| ▸ | GFER | P55789 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 10/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4605007 | 1.00 | ITGA4 (1.00) | ITGA4ITGB7MEN1KMT2APOLB | |
| SCHEMBL14444644 | 0.88 | MEN1 (1.00) | ITGA4ITGB7MEN1KMT2APOLB | |
| SCHEMBL30457527 | 0.88 | MEN1 (1.00) | ITGA4ITGB7MEN1KMT2APOLB | |
| SCHEMBL25633642 | 0.85 | ITGA4 (0.73) | ITGA4ITGB7MEN1KMT2APOLB | |
| SCHEMBL30457669 | 0.85 | ITGA4 (0.73) | ITGA4ITGB7MEN1KMT2APOLB | |
| SCHEMBL1061856 | 0.84 | KMT2A (0.75) | ITGA4ITGB7MEN1KMT2APOLB | |
| SCHEMBL1061858 | 0.84 | KMT2A (0.75) | ITGA4ITGB7MEN1KMT2APOLB | |
| SCHEMBL2981309 | 0.83 | ITGA4 (0.71) | ITGA4ITGB7MEN1KMT2APOLB | |
| SCHEMBL22095990 | 0.82 | ITGA4 (0.70) | ITGA4ITGB7MEN1KMT2APOLB | |
| SCHEMBL3610125 | 0.82 | ITGA4 (0.69) | ITGA4ITGB7MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845781-B1 | USE OF COMPOUNDS DERIVED FROM PYRIMIDINETRIONE AS ACETYL CHOLINESTERASE INHIBITORS, COMPOSITIONS CONTAINING SAID DERIVATIVES, AND THE USES THEREOF | CENTRE NAT RECH SCIENT (FR) | 2008-07-09 | — | — | EP | claimed |
| EP-1845781-B1 | USE OF COMPOUNDS DERIVED FROM PYRIMIDINETRIONE AS ACETYL CHOLINESTERASE INHIBITORS, COMPOSITIONS CONTAINING SAID DERIVATIVES, AND THE USES THEREOF | CENTRE NAT RECH SCIENT (FR) | 2008-07-09 | — | — | EP | disclosed |