⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9793648 | 0.70 | — | — | |
| SCHEMBL1231856 | 0.67 | — | — | |
| SCHEMBL1369784 | 0.67 | — | — | |
| SCHEMBL28836698 | 0.67 | — | — | |
| SCHEMBL6779736 | 0.67 | — | — | |
| SCHEMBL29695880 | 0.67 | — | — | |
| SCHEMBL28546517 | 0.67 | — | — | |
| SCHEMBL28873843 | 0.66 | — | — | |
| SCHEMBL29249251 | 0.66 | — | — | |
| SCHEMBL14248768 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1944307-A2 | Synthetic Salicylihalamides, Apicularens and Derivatives Thereof | Board of Regents, The University of Texas System (US) | 2008-07-16 | — | — | EP | disclosed |
| US-6936723-B2 | Synthetic salicylihalamides, apicularens and derivatives thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2005-08-30 | — | — | US | disclosed |
| US-20040171672-A1 | Synthetic salicylihalamides, apicularens and derivatives thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2004-09-02 | — | — | US | disclosed |
| US-6734209-B2 | MACROCYCLIC LACTONES HAVING ANTI-CANCER ACTIVITY AND VACUOLAR ATPASE INHIBITORY ACTIVITY | BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM | 2004-05-11 | — | — | US | disclosed |
| US-20040063778-A1 | Synthetic salicylihalamides, apicularens and derivatives thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2004-04-01 | — | — | US | disclosed |
| US-6617348-B1 | Treating or preventing osteoporosis | UT SOUTHWESTERN MEDICAL CENTER | 2003-09-09 | — | — | US | disclosed |
| EP-1307439-A2 | SYNTHETIC SALICYLIHALAMIDES, APICULARENS AND DERIVATIVES THEREOF | Board of Regents, The University of Texas System (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002012223-A2 | SYNTHETIC SALICYLIHALAMIDES, APICULARENS AND DERIVATIVES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-02-14 | — | — | WO | disclosed |