Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3291435 | 0.97 | MAPT (0.32) | MAPTCYP1A2CYP3A4CYP2D6THRB | |
| SCHEMBL5589083 | 0.85 | MAPT (0.38) | MAPTCYP1A2CYP3A4CYP2D6THRB | |
| SCHEMBL27993714 | 0.84 | NR4A1 (0.47) | MAPTCYP1A2CYP3A4CYP2C9PKM | |
| SCHEMBL5588853 | 0.84 | MAPT (0.37) | MAPTCYP1A2CYP3A4CYP2D6THRB | |
| SCHEMBL16077908 | 0.81 | TDP1 (0.33) | G6PD | |
| SCHEMBL5587992 | 0.81 | MAPT (0.40) | MAPTCYP1A2CYP3A4CYP2D6THRB | |
| SCHEMBL8089705 | 0.81 | MAPT (0.40) | MAPTCYP1A2CYP3A4CYP2D6THRB | |
| SCHEMBL20337312 | 0.80 | MAPT (0.39) | MAPTCYP1A2CYP3A4CYP2D6THRB | |
| SCHEMBL5587603 | 0.80 | MAPT (0.39) | MAPTCYP1A2CYP3A4CYP2D6THRB | |
| SCHEMBL20337311 | 0.80 | MAPT (0.39) | MAPTCYP1A2CYP3A4CYP2D6THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943281-A1 | HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE | Basell Polyolefine GmbH (DE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007042252-A1 | HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE | BASELL POLYOLEFINE GMBH (DE) | 2007-04-19 | — | — | WO | disclosed |