SCHEMBL8089705

SCHEMBL8089705

CC(C)c1ccccc1/N=C/c1cccc(/C=N/c2ccccc2C(C)C)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.40
ALDH1A1 P00352 2/20 0.40
PLA2G1B P04054 1/20 0.40
ATG4B Q9Y4P1 1/20 0.40
SIGMAR1 Q99720 6/20 0.38
NOS3 P29474 2/20 0.36
NOS1 P29475 2/20 0.36
NOS2 P35228 2/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 2/20 0.36
HIF1A Q16665 2/20 0.36
CYP2D6 P10635 1/20 0.36
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5587992 1.00 MAPT (0.40) MAPTALDH1A1PLA2G1BATG4BSIGMAR1
SCHEMBL20337312 0.98 MAPT (0.39) MAPTALDH1A1PLA2G1BATG4BSIGMAR1
SCHEMBL5587603 0.98 MAPT (0.39) MAPTALDH1A1PLA2G1BATG4BSIGMAR1
SCHEMBL20337311 0.98 MAPT (0.39) MAPTALDH1A1PLA2G1BATG4BSIGMAR1
Hydrochloric Acid SCHEMBL20337306 0.97 ALDH1A1 (0.38) MAPTALDH1A1PLA2G1BATG4BSIGMAR1
Hydrochloric Acid SCHEMBL28685917 0.97 ALDH1A1 (0.38) MAPTALDH1A1PLA2G1BATG4BSIGMAR1
SCHEMBL20337307 0.94 MAPT (0.37) MAPTALDH1A1PLA2G1BATG4BSIGMAR1
Acetone SCHEMBL28791784 0.91 ALDH1A1 (0.39) MAPTALDH1A1PLA2G1BATG4BSIGMAR1
Acetone SCHEMBL28791786 0.91 ALDH1A1 (0.39) MAPTALDH1A1PLA2G1BATG4BSIGMAR1
SCHEMBL27993966 0.83 NR4A1 (0.54) ALDH1A1CYP1A2CYP3A4CYP2C9PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3562799-B1 ETHYLENE OLIGOMERIZATION PROCESSES CHEVRON PHILLIPS CHEMICAL CO LP (US) 2023-08-23 EP claimed
US-11358914-B2 Ethylene oligomerization processes CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2022-06-14 US claimed
US-20210214289-A1 Ethylene Oligomerization Processes CHEVRON PHILLIPS CHEMICAL COMPANY LP 2021-07-15 US claimed
US-10793489-B2 Ethylene oligomerization processes CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2020-10-06 US claimed
US-10604457-B2 Ethylene oligomerization processes CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2020-03-31 US claimed
US-20200095178-A1 Ethylene Oligomerization Processes CHEVRON PHILLIPS CHEMICAL COMPANY LP 2020-03-26 US claimed
EP-3562800-A1 ETHYLENE OLIGOMERIZATION PROCESSES Chevron Phillips Chemical Company LP (US) 2019-11-06 EP claimed
EP-3562799-A1 ETHYLENE OLIGOMERIZATION PROCESSES Chevron Phillips Chemical Company LP (US) 2019-11-06 EP claimed
EP-3562798-A1 ETHYLENE OLIGOMERIZATION PROCESSES Chevron Phillips Chemical Company LP (US) 2019-11-06 EP claimed
US-20190276377-A1 Ethylene Oligomerization Processes CHEVRON PHILLIPS CHEMICAL COMPANY LP 2019-09-12 US claimed
US-10407360-B2 Ethylene oligomerization processes CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2019-09-10 US claimed
US-20190194089-A1 Ethylene Oligomerization Processes CHEVRON PHILLIPS CHEMICAL COMPANY LP 2019-06-27 US claimed
WO-2018128861-A1 ETHYLENE OLIGOMERIZATION PROCESSES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-07-12 WO claimed
WO-2018125826-A1 ETHYLENE OLIGOMERIZATION PROCESSES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-07-05 WO claimed
US-20180186709-A1 Ethylene Oligomerizaton Processes CHEVRON PHILLIPS CHEMICAL COMPANY LP 2018-07-05 US claimed
WO-2018125824-A1 ETHYLENE OLIGOMERIZATION PROCESSES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-07-05 WO claimed
US-20180186708-A1 Ethylene Oligomerization Processes CHEVRON PHILLIPS CHEMICAL COMPANY LP 2018-07-05 US claimed
EP-3562799-B1 ETHYLENE OLIGOMERIZATION PROCESSES CHEVRON PHILLIPS CHEMICAL CO LP (US) 2023-08-23 EP disclosed
US-20140275429-A1 METHOD FOR PRODUCING OLEFIN BLOCK POLYMER USING PLURALITY OF TYPES OF TRANSITION METAL CATALYSTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-18 US disclosed
EP-1059313-A1 Transition metal catalyst component for polymerization, aromatic vinyl compound-olefin copolymer and process for its production by means of the catalyst component DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180186708-A1 Ethylene Oligomerization Processes MAX, AP1M1, AP2M1 MAPT 922/4885ALDH1A1 4669/4885PLA2G1B 1049/4885
US-20190276377-A1 Ethylene Oligomerization Processes NOD2, AP1M1, AP2M1 MAPT 2760/4885ALDH1A1 4471/4885PLA2G1B 4671/4885
US-20190194089-A1 Ethylene Oligomerization Processes NOD2, AP1M1, AP2M1 MAPT 2760/4885ALDH1A1 4471/4885PLA2G1B 4671/4885
US-10793489-B2 Ethylene oligomerization processes NOD2, AP1M1, AP2M1 MAPT 2760/4885ALDH1A1 4471/4885PLA2G1B 4671/4885
US-10604457-B2 Ethylene oligomerization processes EPS15, PICALM, AP2M1 MAPT 1342/4885ALDH1A1 4824/4885PLA2G1B 4132/4885
US-10407360-B2 Ethylene oligomerization processes NOD2, AP1M1, AP2M1 MAPT 2760/4885ALDH1A1 4471/4885PLA2G1B 4671/4885
US-20200095178-A1 Ethylene Oligomerization Processes NOD2, AP1M1, AP2M1 MAPT 2760/4885ALDH1A1 4471/4885PLA2G1B 4671/4885
US-20180186709-A1 Ethylene Oligomerizaton Processes PICALM, EPS15, EPN1 MAPT 1506/4885ALDH1A1 4825/4885PLA2G1B 4217/4885
US-20210214289-A1 Ethylene Oligomerization Processes MAX, AP1M1, AP2M1 MAPT 922/4885ALDH1A1 4669/4885PLA2G1B 1049/4885
US-11358914-B2 Ethylene oligomerization processes MAX, AP1M1, AP2M1 MAPT 922/4885ALDH1A1 4669/4885PLA2G1B 1049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.