Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 8/20 | 0.62 |
| ▸ | HTR3A | P46098 | 4/20 | 0.62 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | WNT1 | P04628 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604965 | 1.00 | CHRNA7 (0.62) | CHRNA7HTR3AUSP30DYRK1AWNT1 | |
| SCHEMBL10225304 | 0.84 | CHRNA7 (0.64) | CHRNA7HTR3AUSP30DYRK1A | |
| SCHEMBL491957 | 0.84 | CHRNA7 (0.64) | CHRNA7HTR3AUSP30DYRK1A | |
| SCHEMBL261646 | 0.82 | CHRNA7 (0.77) | CHRNA7HTR3ADYRK1AHTR3EHTR3B | |
| SCHEMBL2454962 | 0.82 | CHRNA7 (0.77) | CHRNA7HTR3ADYRK1AHTR3EHTR3B | |
| SCHEMBL261083 | 0.82 | CHRNA7 (0.77) | CHRNA7HTR3ADYRK1AHTR3EHTR3B | |
| SCHEMBL1965653 | 0.81 | CHRNA7 (0.63) | CHRNA7HTR3AUSP30DYRK1AWNT1 | |
| SCHEMBL1967392 | 0.81 | CHRNA7 (0.63) | CHRNA7HTR3AUSP30DYRK1AWNT1 | |
| SCHEMBL1966617 | 0.81 | CHRNA7 (0.63) | CHRNA7HTR3AUSP30DYRK1AWNT1 | |
| SCHEMBL12339925 | 0.81 | CHRNA7 (0.74) | CHRNA7HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940833-A1 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, PYRAZOLOPYRIDINES, ISOTHIAZOLOPYRIDINES, AND PREPARATION AND USES THEREOF | Memory Pharmaceuticals Corporation (US) | 2008-07-09 | — | — | EP | claimed |
| WO-2007038367-A1 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, PYRAZOLOPYRIDINES, ISOTHIAZOLOPYRIDINES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2007-04-05 | — | — | WO | claimed |
| EP-1940833-A1 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, PYRAZOLOPYRIDINES, ISOTHIAZOLOPYRIDINES, AND PREPARATION AND USES THEREOF | Memory Pharmaceuticals Corporation (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007038367-A1 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, PYRAZOLOPYRIDINES, ISOTHIAZOLOPYRIDINES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |