SCHEMBL460584

SCHEMBL460584

C=CC(OCC)c1ccccc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
POLB P06746 1/20 0.36
PTPN2 P17706 1/20 0.35
PTPN1 P18031 1/20 0.35
ACHE P22303 4/20 0.34
PTPN9 P43378 1/20 0.33
GAA P10253 2/20 0.32
KDM4E B2RXH2 2/20 0.32
BCHE P06276 1/20 0.32
TYR P14679 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1021604 0.80 GABRA1 (0.47) TSHRGABRA1GABRB2CA12CA1
SCHEMBL5380106 0.76 TSHR (0.55) TSHRGABRA1GABRB2CA12CA1
Ether SCHEMBL10505755 0.75 TSHR (0.46) TSHRGABRA1GABRB2CA12CA1
SCHEMBL11434362 0.74 CASR (0.40) TSHRPOLBKDM4EL3MBTL1MEN1
SCHEMBL2219317 0.74 TSHR (0.59) TSHRGABRA1GABRB2CA12CA1
SCHEMBL22444462 0.73 TSHR (0.57) TSHRGABRA1GABRB2CA12CA1
SCHEMBL3478188 0.72 GABRA1 (0.38) TSHRGABRA1GABRB2CA12CA1
SCHEMBL22444530 0.70 TSHR (0.48) TSHRGABRA1GABRB2CA12CA1
SCHEMBL1956043 0.70 TSHR (0.48) TSHRGABRA1GABRB2POLBACHE
SCHEMBL11394641 0.70 GABRA1 (0.41) TSHRGABRA1GABRB2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053277-B1 COMPOSITE PARTICLES CONTAINING AN ACTIVE SUBSTANCE RHODIA CHIMIE SA (FR) 2003-01-22 EP claimed
US-6054525-A DISSOLVING PLANT MATERIAL CONTAINING POLYISOPRENE IN A SINGLE PHASE MIXED SOLVENT OF A HYDROCARBON SOLVENT AND ORGANIC POLAR SOLVENT TO FORM A MISCELLA; RAISING CONCENTRATION OF POLAR SOLVENT TO PRECIPITATE NATURAL ISOPRENE FROM MISCELLA THE UNIVERSITY OF AKRON (US) 2000-04-25 US claimed
WO-1998011157-A1 HYPOALLERGENIC NATURAL RUBBER LATEX AND A PROCESS FOR MAKING THE SAME THE UNIVERSITY OF AKRON (US) 1998-03-19 WO claimed
EP-0720638-A1 MICROWAVE-ACTIVATED THERMAL STORAGE MATERIAL ThermaStor Technologies, Ltd. (US) 1996-07-10 EP claimed
EP-0494297-B1 GALENICAL PREPARATION METHOD FOR PREPARING A THERAPEUTICAL COMPOSITION PARTICULARLY BASED ON ASPIRIN PEROVITCH PHILIPPE (FR) 1995-10-18 EP claimed
US-5424519-A Microwaved-activated thermal storage material; and method BATTELLE MEMORIAL INSTITUTE (US) 1995-06-13 US claimed
WO-1995008601-A1 MICROWAVE-ACTIVATED THERMAL STORAGE MATERIAL BATTELLE MEMORIAL INSTITUTE (US) 1995-03-30 WO claimed
EP-0494297-A1 GALENICAL PREPARATION METHOD FOR PREPARING A THERAPEUTICAL COMPOSITION PARTICULARLY BASED ON ASPIRIN. PEROVITCH PHILIPPE (FR) 1992-07-15 EP claimed
EP-0475620-A2 Microemulsion diesel fuel compositions and method of use EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-03-18 EP claimed
WO-1992001444-A1 GALENICAL PREPARATION METHOD FOR PREPARING A THERAPEUTICAL COMPOSITION PARTICULARLY BASED ON ASPIRIN PEROVITCH PHILIPPE (FR) 1992-02-06 WO claimed
EP-0468121-A1 Process for the galenical preparation of a therapeutic composition, in particular based on aspirin Perovitch, Philippe (FR) 1992-01-29 EP claimed
US-4029624-A Emulsion polymerization of acrylate or other vinyl monomers using selected mixtures of soluble salts of certain sulfosuccinic acid half esters AMERICAN CYANAMID COMPANY (US) 1977-06-14 US claimed
US-3947400-A Emulsion polymerization of acrylate or other vinyl monomers using selected mixtures of soluble salts of certain sulfosuccinic acid half esters AMERICAN CYANAMID COMPANY (US) 1976-03-30 US claimed
EP-3388235-B1 METHOD OF MAKING A MULTILAYER STRUCTURE DOW GLOBAL TECHNOLOGIES LLC (US) 2023-12-20 EP disclosed
WO-2023217276-A1 HETEROCYCLIC SUBSTITUTED AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND APPLICATION 青岛清原化合物有限公司 2023-11-16 WO disclosed
WO-2023217275-A1 HETEROCYCLE-SUBSTITUTED AROMATIC COMPOUND, METHOD FOR PREPARING SAME, HERBICIDAL COMPOSITION, AND USE THEREOF 青岛清原化合物有限公司 2023-11-16 WO disclosed
US-4799995-A POLYAMINOPOLYALKYLENEPHOSPHONIC ACID THE DOW CHEMICAL COMPANY (US) 1989-01-24 US disclosed
US-4514444-A Fabric cleaning/conditioning compositions THE PROCTER & GAMBLE COMPANY (US) 1985-04-30 US disclosed
US-4029624-A Emulsion polymerization of acrylate or other vinyl monomers using selected mixtures of soluble salts of certain sulfosuccinic acid half esters AMERICAN CYANAMID COMPANY (US) 1977-06-14 US disclosed
US-3947400-A Emulsion polymerization of acrylate or other vinyl monomers using selected mixtures of soluble salts of certain sulfosuccinic acid half esters AMERICAN CYANAMID COMPANY (US) 1976-03-30 US disclosed