⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5387472 | 1.00 | — | — | |
| SCHEMBL15611615 | 1.00 | — | — | |
| SCHEMBL18662364 | 1.00 | — | — | |
| SCHEMBL21813388 | 0.83 | L3MBTL1 (0.48) | — | |
| SCHEMBL21813386 | 0.83 | L3MBTL1 (0.48) | — | |
| SCHEMBL21813474 | 0.83 | L3MBTL1 (0.48) | — | |
| SCHEMBL21813384 | 0.83 | L3MBTL1 (0.48) | — | |
| SCHEMBL21813476 | 0.83 | L3MBTL1 (0.48) | — | |
| SCHEMBL18141930 | 0.78 | L3MBTL1 (0.58) | — | |
| SCHEMBL21813455 | 0.76 | EPHX2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306067-A1 | Modulators of Chemokine Receptor Activity | WEIGAND KLAUS | 2008-12-11 | — | — | US | disclosed |
| EP-1943235-A1 | ARYLUREA DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Novartis AG (CH) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007048771-A1 | ARYLUREA DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | NOVARTIS AG (CH) | 2007-05-03 | — | — | WO | disclosed |