SCHEMBL4606000

SCHEMBL4606000

OB(O)c1ccccc1-c1c2ccccc2cc2ccccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.43
ALOX5 P09917 1/20 0.42
SOS1 Q07889 1/20 0.41
HTR1A P08908 1/20 0.38
HTR7 P34969 1/20 0.38
ALDH1A1 P00352 4/20 0.38
HPGD P15428 3/20 0.38
HSD17B10 Q99714 3/20 0.38
KDM4E B2RXH2 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CYP1A2 P05177 1/20 0.38
GLA P06280 1/20 0.38
CYP2C19 P33261 1/20 0.38
HIF1A Q16665 2/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
CASP1 P29466 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
GPR84 Q9NQS5 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21102242 0.81 ALDH1A1 (0.46) ALDH1A1HPGDHSD17B10KDM4EMEN1
SCHEMBL17711580 0.80 CES1 (0.47) CES1ALOX5SOS1ALDH1A1HPGD
SCHEMBL701570 0.79 CES1 (0.55) CES1ALOX5SOS1HTR1AHTR7
SCHEMBL556400 0.77 HDAC4 (0.45) ALOX5SOS1CYP1A2CYP2C19HIF1A
SCHEMBL30390526 0.76 ALDH1A1 (0.41) ALOX5ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL590641 0.76 ALDH1A1 (0.41) ALOX5ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL29410295 0.76 ALDH1A1 (0.41) ALOX5ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL5880694 0.74 NQO2 (0.42) CES1ALOX5ALDH1A1HPGDHSD17B10
SCHEMBL4264384 0.74 CES1 (0.50) CES1ALOX5SOS1ALDH1A1HPGD
SCHEMBL8865515 0.74 CYP1A2 (0.52) CES1ALOX5SOS1HTR1AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111087387-B Organic compound, display panel and display device 厦门天马微电子有限公司 2022-04-29 CN disclosed
EP-1993992-A1 TETRAPHENYLNAPHTHALENE DERIVATIVES AND ORGANIC LIGHT EMITTING DIODE USING THE SAME LG Chem, Ltd. (KR) 2008-11-26 EP disclosed
WO-2007105884-A1 TETRAPHENYLNAPHTHALENE DERIVATIVES AND ORGANIC LIGHT EMITTING DIODE USING THE SAME LG CHEM, LTD. (KR) 2007-09-20 WO disclosed