Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4605500 | 0.90 | AKR1C3 (0.48) | AKR1C3NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4603446 | 0.88 | POLB (0.47) | AKR1C3NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4606142 | 0.80 | AKR1C3 (0.46) | AKR1C3HTR1AHTR1DHTR1BNPC1 | |
| SCHEMBL4617066 | 0.79 | AKR1C3 (0.52) | AKR1C3NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4604101 | 0.78 | AKR1C3 (0.45) | AKR1C3HTR1AHTR1DHTR1BNPC1 | |
| SCHEMBL4604616 | 0.71 | HTR2C (0.40) | HTR1ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4606307 | 0.69 | AKR1C3 (0.48) | AKR1C3NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4603316 | 0.69 | MAPK1 (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL4603923 | 0.68 | AKR1C3 (0.46) | AKR1C3NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4605194 | 0.68 | ALDH1A1 (0.50) | AKR1C3NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720825-B1 | ANTHRANILIC ACID DERIVATIVES, METHODS FOR THEIR PREPARATION AND USE AS DHODH INHIBITORS | ACTIVE BIOTECH AB (SE) | 2008-07-09 | — | — | EP | disclosed |
| US-7074831-B2 | Compounds, methods for their preparation and use thereof | ACTIVE BIOTECH AB (SE) | 2006-07-11 | — | — | US | disclosed |
| US-20050187297-A1 | New compounds, methods for their preparation and use thereof | ACTIVE BIOTECH AB (SE) | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187297-A1 | New compounds, methods for their preparation and use thereof | MALT1, TPMT, FUCA1 | AKR1C3 246/4885HTR1A 4284/4885HTR1D 4451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.