Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.64 |
| ▸ | HTR3A | P46098 | 1/20 | 0.64 |
| ▸ | DYRK1A | Q13627 | 14/20 | 0.46 |
| ▸ | GSK3B | P49841 | 12/20 | 0.46 |
| ▸ | CLK2 | P49760 | 2/20 | 0.45 |
| ▸ | CLK3 | P49761 | 2/20 | 0.45 |
| ▸ | WNT1 | P04628 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492823 | 1.00 | CHRNA7 (0.64) | CHRNA7HTR3ADYRK1AGSK3BCLK2 | |
| SCHEMBL2787737 | 0.93 | CHRNA7 (0.64) | CHRNA7HTR3ADYRK1AGSK3BCLK2 | |
| Formic Acid SCHEMBL1965954 | 0.89 | CHRNA7 (0.60) | CHRNA7HTR3ADYRK1AGSK3BCLK2 | |
| SCHEMBL1963239 | 0.88 | CHRNA7 (0.70) | CHRNA7HTR3AGSK3B | |
| SCHEMBL1963670 | 0.88 | CHRNA7 (0.70) | CHRNA7HTR3AGSK3B | |
| SCHEMBL4602686 | 0.87 | CHRNA7 (0.64) | CHRNA7HTR3A | |
| SCHEMBL492754 | 0.87 | CHRNA7 (0.64) | CHRNA7HTR3A | |
| Hydrochloric Acid SCHEMBL1963923 | 0.87 | CHRNA7 (0.69) | CHRNA7HTR3AGSK3B | |
| SCHEMBL491613 | 0.85 | CHRNA7 (0.62) | CHRNA7HTR3A | |
| SCHEMBL1964895 | 0.84 | CHRNA7 (0.65) | CHRNA7HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940833-A1 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, PYRAZOLOPYRIDINES, ISOTHIAZOLOPYRIDINES, AND PREPARATION AND USES THEREOF | Memory Pharmaceuticals Corporation (US) | 2008-07-09 | — | — | EP | claimed |
| WO-2007038367-A1 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, PYRAZOLOPYRIDINES, ISOTHIAZOLOPYRIDINES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2007-04-05 | — | — | WO | claimed |