SCHEMBL4606138

SCHEMBL4606138

C=CC1(C)CC[Si](C)(C)OC1(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL134969 0.79
SCHEMBL29035534 0.71 OPRM1 (0.30)
SCHEMBL242068 0.70
SCHEMBL11647862 0.67
SCHEMBL645823 0.67
SCHEMBL7926950 0.67
Dimethyl Fumarate SCHEMBL14966538 0.66 HCAR2 (0.37)
Dimethyl Fumarate SCHEMBL14935840 0.65 HCAR2 (0.36)
SCHEMBL21679576 0.64
SCHEMBL28287945 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016083233-A1 ALKENYLDIALKYLCARBINOXY-FUNCTIONAL POLYDIORGANOSILOXANES WACKER CHEMIE AG (DE) 2016-06-02 WO disclosed
EP-1363767-B1 RELEASE AGENT COMPOSITION LEXMARK INT INC (US) 2008-07-23 EP disclosed
EP-1363767-A4 RELEASE AGENT COMPOSITION LEXMARK INT INC (US) 2004-11-17 EP disclosed
CN-1484580-A Release agent composition ����˹���ʹ�˾ 2004-03-24 CN disclosed
EP-1363767-A1 RELEASE AGENT COMPOSITION Lexmark International, Inc. (US) 2003-11-26 EP disclosed
US-6458461-B1 POLYSILOXANE RELEASE AGENT; FUSER ROLLS LEXMARK INTERNATIONAL, INC 2002-10-01 US disclosed
US-20020098365-A1 Polysiloxane release agent; fuser rolls LEXMARK INTERNATIONAL, INC. 2002-07-25 US disclosed
WO-2002045950-A1 RELEASE AGENT COMPOSITION LEXMARK INTERNATIONAL, INC. (US) 2002-06-13 WO disclosed