Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4603939 | 0.90 | TGFBR1 (0.55) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL13166090 | 0.90 | MEN1 (0.53) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL3352577 | 0.90 | MEN1 (0.53) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL4604093 | 0.87 | TGFBR1 (0.55) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL3565780 | 0.87 | MEN1 (0.59) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL4603267 | 0.86 | GRM1 (0.54) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL4603315 | 0.86 | GRM1 (0.54) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL4604542 | 0.86 | MEN1 (0.54) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL4604313 | 0.84 | MEN1 (0.63) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL4606456 | 0.82 | TGFBR1 (0.70) | MEN1KMT2APOLBGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753512-B1 | TETRAHYDROPYRIDOTHIOPHENES | NYCOMED GMBH (DE) | 2008-07-09 | — | — | EP | claimed |