Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 17/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4260027 | 0.82 | KDM1A (0.63) | KDM1AMAOBSLC6A4SLC6A3KCNH2 | |
| SCHEMBL3717270 | 0.82 | GRIA4 (0.44) | KDM1ASLC6A3KCNH2KDM1BGRIA4 | |
| SCHEMBL3717272 | 0.82 | GRIA4 (0.44) | KDM1ASLC6A3KCNH2KDM1BGRIA4 | |
| SCHEMBL7898071 | 0.82 | KDM1A (0.63) | KDM1AMAOBSLC6A4SLC6A3KCNH2 | |
| SCHEMBL3717972 | 0.82 | KDM1A (0.63) | KDM1AMAOBSLC6A4SLC6A3KCNH2 | |
| SCHEMBL3717970 | 0.82 | KDM1A (0.63) | KDM1AMAOBSLC6A4SLC6A3KCNH2 | |
| SCHEMBL1645757 | 0.82 | KDM1A (0.63) | KDM1AMAOBSLC6A4SLC6A3KCNH2 | |
| SCHEMBL1643845 | 0.82 | GRIA4 (0.44) | KDM1ASLC6A3KCNH2KDM1BGRIA4 | |
| SCHEMBL3719897 | 0.82 | GRIA4 (0.44) | KDM1ASLC6A3KCNH2KDM1BGRIA4 | |
| SCHEMBL17864289 | 0.82 | KDM1A (0.63) | KDM1AMAOBSLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | claimed |
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | disclosed |
| US-6639107-B1 | Potentiating glutamate receptor function | ELI LILLY AND COMPANY | 2003-10-28 | — | — | US | disclosed |