SCHEMBL4607284

SCHEMBL4607284

C=Cc1ccc(CNC(C)=O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.58
HDAC1 Q13547 3/20 0.54
HDAC6 Q9UBN7 1/20 0.54
ALDH1A1 P00352 4/20 0.53
MAPT P10636 2/20 0.53
POLB P06746 1/20 0.53
RAB9A P51151 1/20 0.53
KDM4E B2RXH2 3/20 0.47
HTT P42858 1/20 0.47
HDAC3 O15379 2/20 0.46
HDAC2 Q92769 2/20 0.46
TGM2 P21980 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
VHL P40337 1/20 0.44
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
HTR2B P41595 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23565249 0.84 TPSAB1 (0.47) KMT2AALDH1A1RAB9ATGM2
SCHEMBL12133623 0.84 KMT2A (0.76) KMT2AHDAC1HDAC6ALDH1A1MAPT
SCHEMBL3113924 0.83 KMT2A (0.59) KMT2AHDAC1HDAC6ALDH1A1MAPT
SCHEMBL14341628 0.83 CYP2D6 (0.50) KMT2AALDH1A1MAPTRAB9ATGM2
SCHEMBL10591308 0.82 KDM4E (0.64) ALDH1A1MAPTRAB9AKDM4EHTR2C
SCHEMBL13864006 0.82 TPSAB1 (0.44) HDAC1HDAC6ALDH1A1POLBHDAC3
SCHEMBL13892539 0.82 TSHR (0.54) HDAC1ALDH1A1MAPTRAB9AHDAC3
SCHEMBL17886070 0.81 CYP2C9 (0.59) KMT2AALDH1A1MAPTPOLBTGM2
SCHEMBL13268095 0.81 KMT2A (0.58) KMT2AHDAC1HDAC6ALDH1A1MAPT
SCHEMBL10660916 0.81 ERCC1 (0.44) KMT2AMAPTTGM2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4349477-A1 HYBRID GRAFTED AND HYPERBRANCHED ANION EXCHANGERS Dionex Corporation (US) 2024-04-10 EP claimed
US-20240110026-A1 HYBRID GRAFTED AND HYPERBRANCHED ANION EXCHANGERS DIONEX CORPORATION 2024-04-04 US claimed
CN-117718084-A Grafted and hyperbranched mixed anion exchangers 戴安公司 2024-03-19 CN claimed
US-20080032116-A1 Organic Polymer Monolith, Process for Preparing the Same, and Uses Thereof SHOWA DENKO K.K. (JP) 2008-02-07 US claimed
CN-1961013-A Organic polymer monolith, process for preparing the same, and uses thereof SHOWA DENKO KK (JP) 2007-05-09 CN claimed
EP-1758945-A1 ORGANIC POLYMER MONOLITH, PROCESS FOR PREPARING THE SAME, AND USES THEREOF Showa Denko K.K. (JP) 2007-03-07 EP claimed
WO-2005116095-A1 ORGANIC POLYMER MONOLITH, PROCESS FOR PREPARING THE SAME, AND USES THEREOF SHOWA DENKO K.K. (JP) 2005-12-08 WO claimed
EP-4349477-A1 HYBRID GRAFTED AND HYPERBRANCHED ANION EXCHANGERS Dionex Corporation (US) 2024-04-10 EP disclosed
US-20240110026-A1 HYBRID GRAFTED AND HYPERBRANCHED ANION EXCHANGERS DIONEX CORPORATION 2024-04-04 US disclosed
CN-117718084-A Grafted and hyperbranched mixed anion exchangers 戴安公司 2024-03-19 CN disclosed
US-20170152347-A1 AMIDE DENDRIMER COMPOSITIONS GENZYME CORP (US) 2017-06-01 US disclosed
US-20160085163-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2016-03-24 US disclosed
US-9188885-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-11-17 US disclosed
WO-2008042222-A2 AMIDE DENDRIMER COMPOSITIONS GENZYME CORPORATION (US) 2008-04-10 WO disclosed
WO-2008027551-A2 DENDRIMER COMPOSITIONS GENZYME CORPORATION (US) 2008-03-06 WO disclosed
US-20080032116-A1 Organic Polymer Monolith, Process for Preparing the Same, and Uses Thereof SHOWA DENKO K.K. (JP) 2008-02-07 US disclosed
WO-2008011047-A2 AMINE DENDRIMERS GENZYME CORPORATION (US) 2008-01-24 WO disclosed
CN-1961013-A Organic polymer monolith, process for preparing the same, and uses thereof SHOWA DENKO KK (JP) 2007-05-09 CN disclosed
EP-1758945-A1 ORGANIC POLYMER MONOLITH, PROCESS FOR PREPARING THE SAME, AND USES THEREOF Showa Denko K.K. (JP) 2007-03-07 EP disclosed
WO-2005116095-A1 ORGANIC POLYMER MONOLITH, PROCESS FOR PREPARING THE SAME, AND USES THEREOF SHOWA DENKO K.K. (JP) 2005-12-08 WO disclosed