Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | AVPR1A | P37288 | 10/20 | 0.57 |
| ▸ | AVPR2 | P30518 | 8/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3822995 | 0.92 | ALDH1A1 (0.61) | ALDH1A1MEN1HTTKMT2ATDP1 | |
| SCHEMBL3811241 | 0.91 | AVPR1A (0.58) | ALDH1A1MEN1HTTKMT2ATDP1 | |
| SCHEMBL14532089 | 0.91 | AVPR1A (0.58) | ALDH1A1MEN1HTTKMT2ATDP1 | |
| SCHEMBL3817695 | 0.90 | ALDH1A1 (0.59) | ALDH1A1MEN1HTTKMT2ATDP1 | |
| SCHEMBL14531717 | 0.90 | ALDH1A1 (0.59) | ALDH1A1MEN1HTTKMT2ATDP1 | |
| SCHEMBL3819290 | 0.89 | ALDH1A1 (0.58) | ALDH1A1MEN1HTTKMT2ATDP1 | |
| SCHEMBL3813718 | 0.89 | ALDH1A1 (0.62) | ALDH1A1MEN1HTTKMT2ATDP1 | |
| SCHEMBL3813588 | 0.88 | ALDH1A1 (0.57) | ALDH1A1MEN1HTTKMT2ATDP1 | |
| SCHEMBL3815182 | 0.88 | AVPR1A (0.55) | ALDH1A1MEN1HTTKMT2ATDP1 | |
| SCHEMBL14532090 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MEN1HTTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948190-A2 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | TRANSTECH PHARMA (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007051810-A2 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | TRANSTECH PHARMA (US) | 2007-05-10 | — | — | WO | disclosed |