Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.51 |
| ▸ | SCN10A | Q9Y5Y9 | 8/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14408027 | 0.86 | KCNH2 (0.52) | SCN10AKCNH2CTSA | |
| SCHEMBL22684975 | 0.81 | NPC1 (0.57) | SCN10AKCNH2SCN5ASCN1ASCN9A | |
| SCHEMBL4513898 | 0.78 | AOC3 (0.45) | AOC3FEN1NPC1ALDH1A1 | |
| SCHEMBL22042175 | 0.77 | SCN10A (0.41) | SCN10AKCNH2SCN5ASCN1ASCN9A | |
| SCHEMBL22042127 | 0.77 | FEN1 (0.43) | SCN10AKCNH2SCN5ASCN1ASCN9A | |
| SCHEMBL19626493 | 0.77 | AOC3 (0.57) | AOC3NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL2406713 | 0.75 | AOC3 (0.48) | AOC3TYK2KITNPC1ALDH1A1 | |
| SCHEMBL14435919 | 0.75 | AOC3 (0.47) | AOC3NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL13680632 | 0.74 | SCN10A (0.47) | SCN10AKCNH2SCN5ASCN1ASCN9A | |
| SCHEMBL17752213 | 0.74 | KIF11 (0.44) | AOC3JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080292608-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2008-11-27 | — | — | US | disclosed |
| US-20080292608-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2008-11-27 | — | — | US | disclosed |
| US-20080292608-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2008-11-27 | — | — | US | disclosed |
| CN-101304993-A | Compounds and compositions as ppar modulators | IRM LLC (BM) | 2008-11-12 | — | — | CN | disclosed |
| EP-1945633-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2008-07-23 | — | — | EP | disclosed |
| US-20070203155-A1 | Compounds And Compositions As Ppar Modulators | IRM LLC (BM) | 2007-08-30 | — | — | US | disclosed |
| US-20070203155-A1 | Compounds And Compositions As Ppar Modulators | IRM LLC (BM) | 2007-08-30 | — | — | US | disclosed |
| US-20070203155-A1 | Compounds And Compositions As Ppar Modulators | IRM LLC (BM) | 2007-08-30 | — | — | US | disclosed |
| CN-1980906-A | Compounds and compositions as PPAR modulators | IRM LLC (BM) | 2007-06-13 | — | — | CN | disclosed |
| WO-2007056497-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2007-05-18 | — | — | WO | disclosed |
| EP-1748993-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005116000-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203155-A1 | Compounds And Compositions As Ppar Modulators | PPARG, PPARA, PPARD | AOC3 4702/4885SCN10A 3266/4885KCNH2 4604/4885 |
| US-20080292608-A1 | Compounds and Compositions as Ppar Modulators | PPARG, PPARA, PPARD | AOC3 4687/4885SCN10A 3135/4885KCNH2 4662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.