SCHEMBL4607576

SCHEMBL4607576

CO[Si](C)(NC(=O)O)OC

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
NPSR1 Q6W5P4 1/20 0.31
PPM1B O75688 1/20 0.30
PTPN1 P18031 1/20 0.30
PPP1CC P36873 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5177247 0.78 ALDH1A1 (0.33) ALDH1A1NPSR1
SCHEMBL4604083 0.74 TSHR (0.36) ALDH1A1NPSR1
SCHEMBL2897337 0.74 GAA (0.41) ALDH1A1
SCHEMBL10929703 0.72 KMT2A (0.36) ALDH1A1
SCHEMBL28157390 0.70 KDM4E (0.34)
SCHEMBL1320483 0.69
SCHEMBL6253574 0.67 NPSR1 (0.36) ALDH1A1NPSR1PPM1BPTPN1PPP1CC
SCHEMBL27553773 0.60 ALDH1A1 (0.54) ALDH1A1NPSR1
SCHEMBL37752 0.60
SCHEMBL8601101 0.59 PPM1B (0.41) ALDH1A1PPM1BPTPN1PPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103694946-A Method for producing silane modified polyurethane sealant by using secondary amino alpha-silane HUBEI BLUESKY NEW MATERIALS INC 2014-04-02 CN claimed
CN-114008164-A Moisture curable composition and method for preparing moisture curable composition 瓦克化学股份公司 2022-02-01 CN disclosed
EP-1943282-B1 PREPARATION OF AMINO-SILANE TERMINATED POLYMER BY USING ORGANIC BISMUTH CATALYST AND CURED POLYMER THEREFROM BY USING NON-TIN CATALYST MOMENTIVE PERFORMANCE MAT INC (US) 2020-03-04 EP disclosed
EP-2518094-B1 Preperartion of amino-silane terminated polymer by using organic bismuth catalyst and cured polymer therefrom by using non-tin catalyst MOMENTIVE PERFORMANCE MAT INC (US) 2017-12-27 EP disclosed
CN-103694946-A Method for producing silane modified polyurethane sealant by using secondary amino alpha-silane HUBEI BLUESKY NEW MATERIALS INC 2014-04-02 CN disclosed
EP-2518094-A1 Preperartion of amino-silane terminated polymer by using organic bismuth catalyst and cured polymer therefrom by using non-tin catalyst Momentive Performance Materials Inc. (US) 2012-10-31 EP disclosed
US-8232362-B2 Preparation of amino-silane terminated polymer by using organic bismuth catalyst and cured polymer therefrom by using non-tin catalyst MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-07-31 US disclosed
EP-1943282-A2 PREPARATION OF AMINO-SILANE TERMINATED POLYMER BY USING ORGANIC BISMUTH CATALYST AND CURED POLYMER THEREFROM BY USING NON-TIN CATALYST Momentive Performance Materials Inc. (US) 2008-07-16 EP disclosed
US-7319128-B2 Reacting hydroxy-terminated polysiloxanes with isocyanato-functional silanes in presence of bismuth/zinc carboxylate catalyst; improved moisture/storage stability WACKER CHEMIE AG (DE) 2008-01-15 US disclosed
WO-2007037915-A2 PREPARATION OF AMINO-SILANE TERMINATED POLYMER BY USING ORGANIC BISMUTH CATALYST AND CURED POLYMER THEREFROM BY USING NON-TIN CATALYST MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-04-05 WO disclosed
US-20070060732-A1 Preparation of amino-silane terminated polymer by using organic bismuth catalyst and cured polymer therefrom by using non-tin catalyst MOMENTIVE PERFORMANCE MATERIALS INC. 2007-03-15 US disclosed
US-20050119436-A1 Preparation of organyloxysilyl-terminated polymers WACKER-CHEMIE GMBH (DE) 2005-06-02 US disclosed