Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.61 |
| ▸ | F2 | P00734 | 3/20 | 0.53 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4605784 | 0.90 | F10 (0.60) | F10F2PLATKLK1 | |
| SCHEMBL4606004 | 0.87 | F10 (0.59) | F10F2KLK1 | |
| SCHEMBL4606330 | 0.82 | F10 (0.58) | F10F2KLK1 | |
| SCHEMBL15911366 | 0.81 | F10 (0.78) | F10F2PLATKLK1 | |
| SCHEMBL3837002 | 0.80 | F10 (0.58) | F10F2PLATKLK1CYP3A4 | |
| SCHEMBL3834004 | 0.80 | F10 (0.58) | F10F2PLATKLK1 | |
| SCHEMBL4607026 | 0.77 | F10 (0.69) | F10F2KLK1 | |
| SCHEMBL1675236 | 0.76 | F10 (1.00) | F10F2PLATKLK1 | |
| SCHEMBL6066443 | 0.74 | F10 (0.62) | F10 | |
| SCHEMBL1455873 | 0.74 | F10 (0.64) | F10F2PLATKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569927-B1 | IMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-07-16 | — | — | EP | claimed |