Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOB | P04114 | 4/20 | 0.36 |
| ▸ | MTTP | P55157 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 6/20 | 0.35 |
| ▸ | CA2 | P00918 | 6/20 | 0.35 |
| ▸ | CA12 | O43570 | 5/20 | 0.35 |
| ▸ | CA7 | P43166 | 5/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4124063 | 0.89 | CA1 (0.39) | CA1CA2CA12CA7CA14 | |
| SCHEMBL7860302 | 0.78 | ELANE (0.39) | APOBMTTPCA1CA2CA12 | |
| SCHEMBL865550 | 0.78 | KDM4E (0.41) | APOBMTTPCA1CA2CA12 | |
| SCHEMBL4607263 | 0.77 | CA1 (0.43) | CA1CA2CA12CA7CA14 | |
| SCHEMBL4607688 | 0.75 | MAPT (0.45) | APOBMTTPCA1CA2CA12 | |
| SCHEMBL19732112 | 0.75 | HSD17B1 (0.40) | ALDH1A1HSD17B1HTT | |
| SCHEMBL21318768 | 0.75 | HSD17B1 (0.40) | KDM4EALDH1A1HSD17B1DRD2 | |
| SCHEMBL17513821 | 0.75 | HSD17B1 (0.40) | ALDH1A1HSD17B1HTT | |
| SCHEMBL20444032 | 0.73 | HSD17B1 (0.39) | ALDH1A1HSD17B1 | |
| SCHEMBL20444031 | 0.73 | HSD17B1 (0.39) | ALDH1A1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487781-B1 | PROCESS FOR PREPARING 2-AMINOINDAN DERIVATIVES | NOVARTIS AG (CH) | 2008-07-23 | — | — | EP | claimed |
| CN-1268605-C | Process for preparing 2-aminoindan derivatives | NOVARTIS AG (CH) | 2006-08-09 | — | — | CN | claimed |
| US-6933410-B2 | Process for preparing 5,6-diethyl-2,3-dihydro-1H-inden-2-amine | NOVARTIS AG (CH) | 2005-08-23 | — | — | US | claimed |
| CN-1639111-A | Process for preparing 2-aminoindan derivatives | NOVARTIS AG (CH) | 2005-07-13 | — | — | CN | claimed |
| US-20030187301-A1 | Process for preparing 5,6-diethyl-2,3-dihydro-1H-inden-2-amine | NOVARTIS AG (CH) | 2003-10-02 | — | — | US | claimed |
| EP-1487781-B1 | PROCESS FOR PREPARING 2-AMINOINDAN DERIVATIVES | NOVARTIS AG (CH) | 2008-07-23 | — | — | EP | disclosed |
| EP-1487781-B1 | PROCESS FOR PREPARING 2-AMINOINDAN DERIVATIVES | NOVARTIS AG (CH) | 2008-07-23 | — | — | EP | disclosed |
| CN-1268605-C | Process for preparing 2-aminoindan derivatives | NOVARTIS AG (CH) | 2006-08-09 | — | — | CN | disclosed |
| US-6933410-B2 | Process for preparing 5,6-diethyl-2,3-dihydro-1H-inden-2-amine | NOVARTIS AG (CH) | 2005-08-23 | — | — | US | disclosed |
| CN-1639111-A | Process for preparing 2-aminoindan derivatives | NOVARTIS AG (CH) | 2005-07-13 | — | — | CN | disclosed |
| US-20030187301-A1 | Process for preparing 5,6-diethyl-2,3-dihydro-1H-inden-2-amine | NOVARTIS AG (CH) | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187301-A1 | Process for preparing 5,6-diethyl-2,3-dihydro-1H-inden-2-amine | NAT1, AADAC, IDH3A | APOB 1740/4885MTTP 3262/4885CA1 2153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.