Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | FDPS | P14324 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4218503 | 1.00 | AKR1C3 (0.39) | AKR1C3POLBKDM4EFDPSKMT2A | |
| SCHEMBL4223938 | 1.00 | AKR1C3 (0.39) | AKR1C3POLBKDM4EFDPSKMT2A | |
| SCHEMBL4219857 | 0.90 | KDM4E (0.47) | AKR1C3POLBKDM4EFDPSKMT2A | |
| SCHEMBL4219853 | 0.90 | KDM4E (0.47) | AKR1C3POLBKDM4EFDPSKMT2A | |
| SCHEMBL4215918 | 0.87 | KDM4E (0.42) | AKR1C3POLBKDM4EKMT2AGAA | |
| SCHEMBL68302 | 0.87 | KDM4E (0.42) | AKR1C3POLBKDM4EKMT2AGAA | |
| SCHEMBL68303 | 0.87 | KDM4E (0.42) | AKR1C3POLBKDM4EKMT2AGAA | |
| SCHEMBL4229402 | 0.86 | POLB (0.38) | POLBKDM4EFDPSKMT2AGAA | |
| SCHEMBL4229405 | 0.85 | FDPS (0.41) | POLBKDM4EFDPSKMT2AGAA | |
| SCHEMBL4218498 | 0.85 | KDM4E (0.39) | POLBKDM4EFDPSKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943213-A2 | PPAR MODULATING BIAROMATIC COMPOUNDS | Galderma Research & Development (FR) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007049158-A2 | PPAR MODULATING BIAROMATIC COMPOUNDS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-05-03 | — | — | WO | disclosed |