Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433126 | 1.00 | ALDH1A1 (0.45) | ALDH1A1NOTUMKMT2AKDM4ETSHR | |
| SCHEMBL1740735 | 0.75 | ALDH1A1 (0.55) | ALDH1A1NOTUMKMT2AKDM4ETSHR | |
| SCHEMBL28425870 | 0.69 | ALDH1A1 (0.60) | ALDH1A1NOTUMKMT2AKDM4ETSHR | |
| SCHEMBL22637403 | 0.66 | ALDH1A1 (0.56) | ALDH1A1NOTUMKMT2AKDM4ETSHR | |
| SCHEMBL430921 | 0.64 | ALDH1A1 (0.61) | ALDH1A1NOTUMKMT2AKDM4ETSHR | |
| SCHEMBL14778436 | 0.63 | ALDH1A1 (0.60) | ALDH1A1NOTUMKMT2AKDM4ETSHR | |
| SCHEMBL22636958 | 0.63 | ALDH1A1 (0.56) | ALDH1A1NOTUMKMT2AKDM4ETSHR | |
| SCHEMBL431148 | 0.63 | ALDH1A1 (0.43) | ALDH1A1NOTUMKMT2AKDM4ETSHR | |
| SCHEMBL10199133 | 0.61 | NOTUM (0.33) | ALDH1A1NOTUM | |
| SCHEMBL430561 | 0.60 | ALDH1A1 (0.43) | ALDH1A1NOTUMKMT2AKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595982-A1 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | Rigel Pharmaceuticals, Inc. (US) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012012619-A1 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | RIGEL PHARMACEUTICALS, INC. (US) | 2012-01-26 | — | — | WO | disclosed |