SCHEMBL460833

SCHEMBL460833

FC=C=CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL575110 0.62
SCHEMBL22750839 0.62
SCHEMBL1135053 0.59
SCHEMBL73110 0.59
SCHEMBL73111 0.59
SCHEMBL775378 0.59
SCHEMBL3170159 0.59
SCHEMBL22750844 0.59
SCHEMBL22750833 0.59
SCHEMBL22750841 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114702417-B Synthesis method for preparing difluoroethylene sulfide by nucleophilic substitution of beta-site of geminal difluoroallene compound 上海毕得医药科技股份有限公司 2024-04-02 CN claimed
CN-117186080-A Chromophore compound, preparation method thereof and application of chromophore compound 华为技术有限公司 2023-12-08 CN claimed
CN-117186079-A Chromophore compound, preparation method thereof and application of chromophore compound 华为技术有限公司 2023-12-08 CN claimed
WO-2023231529-A1 CHROMOPHORE COMPOUND AND PREPARATION METHOD THEREFOR, AND APPLICATION OF CHROMOPHORE COMPOUND 华为技术有限公司 2023-12-07 WO claimed
WO-2023231528-A1 CHROMOPHORE COMPOUND, PREPARATION METHOD THEREFOR, AND USE OF CHROMOPHORE COMPOUND 华为技术有限公司 2023-12-07 WO claimed
CN-114409515-B Preparation method of gem-difluoroolefin compound 南京工业大学 2023-03-21 CN claimed
CN-114702417-A Synthesis method for preparing difluoroethylene sulfide by nucleophilic substitution of beta site of gem-difluoroallene compound 上海毕得医药科技股份有限公司 2022-07-05 CN claimed
CN-114409515-A Preparation method of gem-difluoroolefin compound 南京工业大学 2022-04-29 CN claimed
CN-111155141-B Method for electrochemically synthesizing gem-difluoroolefin 中国科学技术大学 2022-01-11 CN claimed
CN-113683481-A Substituted monofluoroallene compound, preparation method and application thereof 南昌大学 2021-11-23 CN claimed
US-20060052643-A1 Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes UNIVERSITY OF SOUTHERN CALIFORNIA 2006-03-09 US claimed
WO-2005097739-A2 NUCLEOPHILIC SUBSTITUTION REACTIONS OF DIFLUOROMETHYL PHENYL SULFONE WITH ALKYL HALIDES LEADING TO THE FACILE SYNTHESIS OF TERMINAL 1,1-DIFLUORO-1-ALKENES AND DIFLUOROMETHYLALKANES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2005-10-20 WO claimed
US-20040248872-A1 Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2004-12-09 US claimed
EP-1439169-A1 DIFLUOROALKENE DERIVATIVE&amp;comma; PEST CONTROL AGENT CONTAINING THE SAME&amp;comma; AND INTERMEDIATE THEREFOR KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2004-07-21 EP claimed
US-6585953-B2 Synthesis of 17F labeled fluoroalkanes WISCONSIN ALUMNI RESEARCH FOUNDATION 2003-07-01 US claimed
EP-1315689-A1 SYNTHESIS OF 17F LABELED FLUOROALKANES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2003-06-04 EP claimed
WO-2002020434-A1 SYNTHESIS OF 17F LABELED FLUOROALKANES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2002-03-14 WO claimed
US-20020028177-A1 Synthesis of 17F labeled fluoroalkanes NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-03-07 US claimed
EP-0406748-B1 Dehydrofluorination and dehydrogenation of fluorinated alkanes ATOCHEM NORTH AMERICA (US) 1994-09-28 EP claimed
EP-0406748-A2 Dehydrofluorination and dehydrogenation of fluorinated alkanes ATOCHEM NORTH AMERICA, INC. (US) 1991-01-09 EP claimed