Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11014270 | 0.96 | TSHR (0.42) | TSHRALDH1A1TDP1 | |
| SCHEMBL7071607 | 0.93 | — | — | |
| SCHEMBL1969790 | 0.85 | — | — | |
| SCHEMBL10349808 | 0.85 | ALDH1A1 (0.32) | TSHRALDH1A1TDP1 | |
| SCHEMBL8734013 | 0.83 | TSHR (0.68) | TSHRALDH1A1TDP1 | |
| SCHEMBL10687324 | 0.83 | TSHR (0.68) | TSHRALDH1A1TDP1 | |
| SCHEMBL11588200 | 0.83 | TSHR (0.60) | TSHRALDH1A1TDP1 | |
| SCHEMBL11725426 | 0.81 | — | — | |
| SCHEMBL11758638 | 0.78 | — | — | |
| SCHEMBL6433945 | 0.77 | TDP1 (0.43) | TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948646-A2 | SUBSTITUTED PHENYLPIPERIDINES WITH SEROTONINERGIC ACTIVITY AND ENHANCED THERAPEUTIC PROPERTIES | Auspex Pharmaceuticals Inc. (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007058998-A2 | SUBSTITUTED PHENYLPIPERIDINES WITH SEROTONINERGIC ACTIVITY AND ENHANCED THERAPEUTIC PROPERTIES | AUSPEX PHARMACEUTICALS, INC. (US) | 2007-05-24 | — | — | WO | disclosed |
| US-5354768-A | Use of imidazopyrazole derivatives as analgesics and anti-inflammatory agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-11 | — | — | US | disclosed |