SCHEMBL4608367

SCHEMBL4608367

C=CCOc1ccccc1N

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.55
TSHR P16473 3/20 0.51
HSD17B10 Q99714 2/20 0.51
HPGD P15428 1/20 0.51
MAPK1 P28482 1/20 0.51
CYP1A2 P05177 2/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
LIG1 P18858 1/20 0.49
CYP3A4 P08684 1/20 0.46
CYP2A6 P11509 1/20 0.46
APP P05067 1/20 0.46
ADRA2B P18089 2/20 0.45
PTGS1 P23219 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
LMNA P02545 2/20 0.44
RECQL P46063 1/20 0.44
KDM4E B2RXH2 1/20 0.44
SLC22A1 O15245 1/20 0.43
ADRB2 P07550 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Diallyloxybenzene SCHEMBL366516 0.84 HPGD (0.60) ALDH1A1TSHRHSD17B10HPGDMAPK1
1,2-Diallyloxybenzene SCHEMBL29768784 0.84 HPGD (0.60) ALDH1A1TSHRHSD17B10HPGDMAPK1
SCHEMBL9671334 0.84 TSHR (0.45) ALDH1A1TSHRHSD17B10HPGDMAPK1
SCHEMBL14536869 0.83 ALDH1A1 (0.59) ALDH1A1CYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL20554725 0.81 CYP3A4 (0.49) ALDH1A1TSHRHSD17B10HPGDMAPK1
SCHEMBL12004979 0.81 TSHR (0.42) ALDH1A1TSHRHSD17B10HPGDMAPK1
SCHEMBL26118236 0.81 TSHR (0.53) ALDH1A1TSHRHSD17B10HPGDMAPK1
SCHEMBL16056353 0.80 KDM4E (0.58) ALDH1A1TSHRHSD17B10HPGDMAPK1
SCHEMBL20554231 0.80 TSHR (0.45) ALDH1A1TSHRHSD17B10HPGDMAPK1
SCHEMBL5174782 0.79 HPGD (0.51) ALDH1A1TSHRHSD17B10HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115519842-B Soft sleep-aiding quilt cover fabric and preparation method thereof 江苏斯得福纺织股份有限公司 2024-10-22 CN claimed
CN-115746351-A Low-thermal expansion coefficient thermoplastic polyimide film and preparation method thereof 安徽国风新材料股份有限公司 2023-03-07 CN claimed
CN-115519842-A Soft sleep-aiding quilt cover fabric and preparation method thereof 江苏斯得福纺织股份有限公司 2022-12-27 CN claimed
CN-113151919-B Fiber and disc for biological rotating disc and preparation method 马东兵 2022-08-23 CN claimed
CN-113151919-A Fiber and disc for biological rotating disc and preparation method 马东兵 2021-07-23 CN claimed
CN-112391162-A Luminescent material and quantum dot film and preparation method thereof TCL集团股份有限公司 2021-02-23 CN claimed
EP-0287478-B1 PROCESS FOR PREPARING AROMATIC DIAMINES CONTAINING POLYDIORGANOSILOXANE GROUPS RHONE-POULENC CHIMIE (FR) 1992-05-13 EP claimed
US-4948858-A Preparation of diorganopolysiloxylated diamines RHONE-POULENC CHIMIE (FR) 1990-08-14 US claimed
EP-0287478-A1 Process for preparing aromatic diamines containing polydiorganosiloxane groups RHONE-POULENC CHIMIE (FR) 1988-10-19 EP claimed
EP-0271170-A2 Herbicidal substituted benzofurans and benzopyrans SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-06-15 EP claimed
JP-1157940-A None JP disclosed
JP-56071047-A None JP disclosed
JP-6293817-A None JP disclosed
JP-1242562-A None JP disclosed
CN-115519842-B Soft sleep-aiding quilt cover fabric and preparation method thereof 江苏斯得福纺织股份有限公司 2024-10-22 CN disclosed
US-4330542-A N(Sulfonyl)anilines for treating angina pectoris SANOFI (FR) 1982-05-18 US disclosed
JP-S5671047-A PREPARATION OF AMINOPHENOL ALKYL ETHER NIPPON NOHYAKU CO LTD 1981-06-13 JP disclosed
US-4231963-A ETHERIFICATION OF ALKALI METAL AMINOPHENOLATE IHARA CHEMICAL INDUSTRY COMPANY, LIMITED (JP) 1980-11-04 US disclosed
US-4128561-A Process for the preparation of 2-(2-thienyl)-ethylamine and derivatives thereof PARCOR (FR) 1978-12-05 US disclosed
US-3978091-A FUNGICIDES, INSECTICIDES, NEMATOCIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) 1976-08-31 US disclosed