Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | USP2 | O75604 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3811232 | 0.87 | CNR2 (0.45) | NSD2TDP1HSD11B1CNR2HSD17B1 | |
| SCHEMBL3811387 | 0.85 | HSD11B1 (0.53) | TDP1KDM4EHSD11B1CNR2HSD17B1 | |
| SCHEMBL3815228 | 0.83 | NSD2 (0.47) | NSD2CYP3A4ALDH1A1CYP2C19CYP2C9 | |
| SCHEMBL3810933 | 0.81 | KMT2A (0.48) | TDP1KDM4EHSD11B1HTTALDH1A1 | |
| SCHEMBL3810934 | 0.80 | HSD11B1 (0.56) | TDP1HSD11B1HSD17B1KMT2ASMN1; SMN2 | |
| SCHEMBL3818382 | 0.75 | HDAC1 (0.55) | ALDH1A1TSHRHPGDKMT2ALIMK2 | |
| SCHEMBL3813361 | 0.74 | NSD2 (0.49) | NSD2ALDH1A1HPGDKMT2A | |
| SCHEMBL3814572 | 0.73 | NSD2 (0.42) | NSD2CNR2CASRMAPK1HCRTR1 | |
| SCHEMBL3813497 | 0.72 | SMN1; SMN2 (0.55) | TDP1HTTALDH1A1HPGDKMT2A | |
| SCHEMBL3809571 | 0.70 | KMT2A (0.42) | HTTUSP2ALDH1A1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948190-A2 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | TRANSTECH PHARMA (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007051810-A2 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | TRANSTECH PHARMA (US) | 2007-05-10 | — | — | WO | disclosed |