Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23610328 | 0.84 | ALDH1A1 (0.47) | GAAL3MBTL1ALDH1A1KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL6195686 | 0.80 | CYP19A1 (0.43) | L3MBTL1ALDH1A1KDM4EFFAR1MAPT | |
| SCHEMBL12090214 | 0.80 | CHRNA7 (0.56) | — | |
| SCHEMBL6963115 | 0.78 | NR3C2 (0.48) | ALDH1A1KDM4ETSHRMAPTHRH3 | |
| SCHEMBL10770146 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KDM4ETSHRMAPTHRH3 | |
| SCHEMBL3180491 | 0.75 | FFAR1 (0.60) | FFAR1HRH3SLC18A3 | |
| SCHEMBL6674309 | 0.75 | DPP4 (0.45) | GAAL3MBTL1ALDH1A1KDM4EFFAR1 | |
| SCHEMBL1445163 | 0.75 | DYRK1A (0.43) | GAAL3MBTL1ALDH1A1KDM4ETSHR | |
| SCHEMBL13879514 | 0.75 | ALDH1A1 (0.60) | GAAALDH1A1TSHRMAPTHSD17B10 | |
| SCHEMBL28403533 | 0.75 | HRH3 (0.53) | GAAL3MBTL1ALDH1A1KDM4EFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948636-A2 | COMPOUNDS AND COMPOSITIONS AS LXR MODULATORS | IRM LLC (BM) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007092065-A2 | COMPOUNDS AND COMPOSITIONS AS LXR MODULATORS | IRM LLC (BM) | 2007-08-16 | — | — | WO | disclosed |