Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Dexborneol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Borneol SCHEMBL1819628 | 1.00 | EPHX2 (0.43) | EPHX2KMT2AMAPTMAPK1CYP2C19 | |
| Dexborneol SCHEMBL1819627 | 1.00 | EPHX2 (0.43) | EPHX2KMT2AMAPTMAPK1CYP2C19 | |
| Borneol SCHEMBL28002051 | 1.00 | EPHX2 (0.43) | EPHX2KMT2AMAPTMAPK1CYP2C19 | |
| Dexborneol SCHEMBL17144628 | 0.94 | EPHX2 (0.44) | EPHX2KMT2AMAPTMAPK1ALDH1A1 | |
| Borneol SCHEMBL17144629 | 0.94 | EPHX2 (0.44) | EPHX2KMT2AMAPTMAPK1ALDH1A1 | |
| Borneol SCHEMBL28225316 | 0.93 | EPHX2 (0.39) | EPHX2KMT2AMAPTMAPK1CYP2C19 | |
| Borneol SCHEMBL28045046 | 0.93 | EPHX2 (0.42) | EPHX2ALDH1A1LMNA | |
| Dexborneol SCHEMBL10466945 | 0.92 | EPHX2 (0.43) | EPHX2KMT2AMAPTMAPK1CYP2C19 | |
| Dexborneol SCHEMBL10465343 | 0.92 | EPHX2 (0.43) | EPHX2KMT2AMAPTMAPK1CYP2C19 | |
| Borneol SCHEMBL10465345 | 0.92 | EPHX2 (0.43) | EPHX2KMT2AMAPTMAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024239611-A1 | PREPARATION METHOD FOR MODIFIED NICKEL PASTE FOR MLCC | 畅的新材料科技（上海）有限公司 | 2024-11-28 | — | — | WO | claimed |
| CN-111979047-B | Essence microcapsule and disinfectant containing essence microcapsule | 宁波芬畅凝科香精香料有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-114196475-A | Ginger flower essence | 上海应用技术大学 | 2022-03-18 | — | — | CN | claimed |
| CN-110194717-B | Method for producing camphorquinone by using by-product generated in camphor synthesis process as raw material | 宁夏万香源生物科技有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-113150864-B | Natural and fresh flower and fruit flavor essence and preparation method and application thereof | 广州芬豪香精有限公司 | 2021-11-02 | — | — | CN | claimed |
| CN-113150864-A | Natural and fresh flower and fruit flavor essence and preparation method and application thereof | 广州芬豪香精有限公司 | 2021-07-23 | — | — | CN | claimed |
| CN-111391515-B | Organometallic compound resistor thermal print head substrate and manufacturing method thereof | 山东华菱电子股份有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-111979047-A | Essence microcapsule and disinfectant containing essence microcapsule | 宁波芬畅凝科香精香料有限公司 | 2020-11-24 | — | — | CN | claimed |
| CN-111391515-A | MO heating resistor body thermal-sensitive printing head substrate and manufacturing method | 山东华菱电子股份有限公司 | 2020-07-10 | — | — | CN | claimed |
| EP-1979416-A2 | SILICONE ADDITIVES FOR COMPATABILIZING ORGANIC COMPOUNDS WITH WAX MIXTURES | Momentive Performance Materials Inc. (US) | 2008-10-15 | — | — | EP | claimed |
| US-20080028670-A1 | SILICONE ADDITIVES FOR COMPATALIZING ORGANIC COMPOUNDS WITH WAX MIXTURES | GENERAL ELECTRIC COMPANY (US) | 2008-02-07 | — | — | US | claimed |
| WO-2007075537-A2 | SILICONE ADDITIVES FOR COMPATABILIZING ORGANIC COMPOUNDS WITH WAX MIXTURES | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2007-07-05 | — | — | WO | claimed |
| WO-2025043944-A1 | USE OF ESTER COMPOUND AND RELATED EXTRACT AS BIOSTIMULANT | 成都新朝阳作物科学股份有限公司 | 2025-03-06 | — | — | WO | disclosed |
| WO-2024239611-A1 | PREPARATION METHOD FOR MODIFIED NICKEL PASTE FOR MLCC | 畅的新材料科技（上海）有限公司 | 2024-11-28 | — | — | WO | disclosed |
| CN-112920013-B | Turpentine synthesized fatty acid borneol ester, preparation method and application thereof in preparation of borneol | 广西壮族自治区林业科学研究院 | 2023-04-07 | — | — | CN | disclosed |
| CN-111979047-B | Essence microcapsule and disinfectant containing essence microcapsule | 宁波芬畅凝科香精香料有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-1633278-A | anti-wrinkle cosmetic bag | UNILEVER HOME & PERSONAL CARE (NL) | 2005-06-29 | — | — | CN | disclosed |
| US-20040009245-A1 | Methods and apparatus to prevent, treat and cure infections of the human respiratory system by pathogens causing severe acute respiratory syndrome (SARS) | INHALATION, INC. | 2004-01-15 | — | — | US | disclosed |
| CN-1408696-A | Method for producing camphor by sulfuric acid catalyzed camphene hydration | TANG SONGBAI (CN) | 2003-04-09 | — | — | CN | disclosed |
| US-6447816-B1 | Methods and apparatus to prevent colds, flus, and infections of the human respiratory system | INHALATION, INC. | 2002-09-10 | — | — | US | disclosed |